Sensitizing effects of gallium citrate on hyperthermic cell killing in vitro

International Journal of Hyperthermia

Volumn 16, Issue 5, 2000, Pages 457-470

  Miyazaki, N ^a   Nakano, H ^a   Kawakami, N ^a   Kugotani, M ^a   Nishihara, K ^a   Aoki, Y ^a   Shinohara, K ^a  

^a TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE   (Japan)

Author keywords

ATP; Cultured cells; Gallium citrate; Hyperthermia; Sensitization

Indexed keywords

ADENOSINE TRIPHOSPHATE; GALLIUM CITRATE;

ANIMAL CELL; ARTICLE; CARCINOMA CELL; CELL CULTURE; CELL KILLING; CELL SURVIVAL; CELL VIABILITY; HELA CELL; HYPERTHERMIA; IN VITRO STUDY; LEUKEMIA L 5178 Y; LEUKEMIA P 388; MOUSE; NONHUMAN; SENSITIZATION;

EID: 0033811691     PISSN: 02656736     EISSN: None     Source Type: Journal    
DOI: 10.1080/026567300416767     Document Type: Article

References (34)

1. Studies on the antitumor activity of gallium nitrate (NSC-15200) and other group IIIa metal salts
2. Sensitization to hyperthermia by 3,3'-dipentyloxcarbocyanine iodide: A positive correlation with DNA damage and negative correlations with altered cell morphology, oxygen consumption inhibition, and reduced ATP levels
3. Effects of different transferrin forms on transferrin receptor expression, iron uptake and cellular proliferation of human leukemic HL60 cells
4. Uptake of gallium-67 by human leukemic cells: Demonstration of transferrin receptor-dependent and transferrin-independent mechanisms
5. Inhibition of leukemic HL60 cell growth by transferrin-gallium: Effects on ribonucleotide reductase and demonstration of drug synergy with hydroxyurea
6. 67Ga citrate
7. Gallium nitrate: The second metal with clinical activity
8. The continuing clinical role of gallium 67 scintigraphy in the age of receptor imaging
9. Hyperthermia in cancer therapy: The biological basis and unresolved questions
10. Induction of apoptosis by iron deprivation in human leukemic CCRF-CEM cells
11. Toxicity and antitumor activity of gallium nitrate and periodically related metal salts
12. Gallium nitrate
13. Therapeutic potential of intravenous 67-gallium in non-Hodgkin's lymphoma
14. Radiotoxicity of 67-gallium on myeloid leukemic blasts
15. High-dose gallium-67 therapy in patients with relapsed acute leukaemia: A feasibility study
16. Gallium-67 imaging: A predictor of residual tumor viability and clinical outcome in patients with diffuse large-cell lymphoma
17. Hyperthermic sensitization by the radical initiator 2,2'-azobis(2-amidinopropane) dihydrochloride (AAPH). 1. In vitro studies
18. Common pathway for tumor cell uptake of gallium-67 and iron-59 via a transferrin receptor
19. Heat-induced thermotolerance expressed in the energy metabolism of mammalian cells
20. A Phase II trial of gallium nitrate (NSC No. 15200) in nonsquamous cell carcinoma of the cervix. A Gynecologic Oncology Group study
21. Effect of gallium on the tyrosyl radical of the iron-dependent M2 subunit of ribonucleotide reductase
22. Tumor cell toxicity of stable gallium nitrate: Enhancement by transferrin and protection by iron
23. Continuous infusion gallium nitrate for patients with advanced refractory urothelial tract tumors
24. The role of ATP metabolism in hyperthermic cell killing
25. Gallium citrate, a new sensitizer of cells to hyperthermia
26. Early changes of adenosine triphosphate levels in L5178Y cells during hyperthermia
27. Mechanism of gallium-67 accumulation in tumors
28. Radiogallium localization in tumors: Blood binding and transport and the role of transferrin
29. Gallium-67 in the human lymphoid cell line U-715: Uptake, cytotoxicity, and intracellular localization
30. Gallium nitrate inhibits calcium resorption from bone and its effective treatment for cancer-related hypercalcemia
31. Treatment of patients with advanced malignant lymphoma using gallium nitrate administered as a seven-day continuous infusion
32. 67Ga localization in malignant disease