Methods for multipoint disease mapping using linkage disequilibrium

Genetic Epidemiology

Volumn 19, Issue SUPPL. 1, 2000, Pages

  Schaid, Daniel J ^a   Rowland, Charles M ^a  

^a MAYO CLINIC   (United States)

Author keywords

Composite likelihood; Linkage disequilibrium; Multipoint gene mapping; Mutation

Indexed keywords

CONFERENCE PAPER; GENE LINKAGE DISEQUILIBRIUM; GENE MAPPING; GENE MUTATION; GENETIC MODEL; HUMAN; MARKER GENE; MAXIMUM LIKELIHOOD METHOD; POPULATION GENETICS; STATISTICAL ANALYSIS;

ALLELES; CHROMOSOME MAPPING; GENETIC DISEASES, INBORN; GENETIC MARKERS; HUMAN; LIKELIHOOD FUNCTIONS; LINKAGE DISEQUILIBRIUM; MUTATION; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0033810402     PISSN: 07410395     EISSN: None     Source Type: Journal    
DOI: 10.1002/1098-2272(2000)19:1+<::AID-GEPI11>3.0.CO;2-D     Document Type: Conference Paper

References (12)

1. Limits of resolution of genetic linkage studies
2. Disequilibrium likelihoods for fine-scale mapping of a rare allele
3. Likelihood methods for locating disease genes in nonequilibrium populations
4. Linkage disequilibrium mapping in isolated founder populations
5. Mapping complex genetic traits in humans: New methods using a complete RFLP linkage map
6. Assessment of linkage disequilibrium by the decay of haplotype sharing, with application to fine-scale genetic mapping
7. Likelihood analysis of disequilibrium mapping and related problems
8. Linkage-disequilibrium mapping of disease genes by reconstruction of ancestral haplotypes in founder populations
9. Gene genealogies within mutant allelic classes
10. A powerful likelihood method for the analysis of linkage disequilibrium between trait loci and one or more polymorphic marker loci
11. Fine-scale genetic mapping based on linkage disequilibrium: Theory and applications