Isolation from rat urine and human liver microsomes and identification by electrospray and nanospray tandem mass spectrometry of new malagashanine metabolites

Journal of Mass Spectrometry

Volumn 35, Issue 9, 2000, Pages 1112-1120

  Rafatro, H ^a   Verbeeck, R K ^b   Gougnard, T Y R ^c   De Jonghe, P J M ^d   Rasoanaivo, P ^e   Laurent, A ^b   Lhost, G ^b  

^a UNIVERSITY OF ANTANANARIVO   (Madagascar)

^b UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

^c UNIVERSITY OF LIÈGE   (Belgium)

^d NATIONAL INSTITUTE FOR PUBLIC HEALTH AND THE ENVIRONMENT   (Netherlands)

^e Inst Malgache de Rech Appl   (Madagascar)

Author keywords

Dihydroindole alkaloids; High performance liquid chromatography; Malagashanine metabolism; Mass spectrometry; Strychnos

Indexed keywords

ANTIMALARIAL AGENT; CHLOROQUINE; DRUG METABOLITE; MALAGASHANINE; QUININE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; DRUG IDENTIFICATION; DRUG ISOLATION; DRUG METABOLISM; DRUG STRUCTURE; HUMAN; HUMAN TISSUE; ISOMERISM; LIVER MICROSOME; MALARIA; MALE; MASS SPECTROMETRY; NONHUMAN; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; RAT; TANDEM MASS SPECTROMETRY; URINE;

ALKALOIDS; ANIMAL; ANTIMALARIALS; CHLOROQUINE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG RESISTANCE; HUMAN; MAGNETIC RESONANCE SPECTROSCOPY; MALE; MICROSOMES, LIVER; RATS; RATS, WISTAR; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SPECTROPHOTOMETRY, ULTRAVIOLET;

EID: 0033807723     PISSN: 10765174     EISSN: None     Source Type: Journal    
DOI: 10.1002/1096-9888(200009)35:9<1112::AID-JMS39>3.0.CO;2-K     Document Type: Article

References (9)