Moxonidine as initial therapy and in combination treatment of essential hypertension: Result of the TOPIC (Trial of Physiotens in combination) study;Moxonidin als initialtherapie und in kombination bei der behandlung der essentiellen hypertonie: Ergebnisse der TOPIC-studie (Trial of Physiotens in combination)

Journal fur Hypertonie

Volumn 4, Issue 3, 2000, Pages 40-51

  Waters, J ^a   Ashford, J ^a   Jager, B ^a   Wonnacott, S ^a   Verboom, C N ^a  

^a Solvay Healthcare Ltd   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AMLODIPINE; ENALAPRIL; HYDROCHLOROTHIAZIDE; MOXONIDINE; NORMOXIN; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; BLOOD PRESSURE REGULATION; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG TOLERABILITY; ESSENTIAL HYPERTENSION; FEMALE; GENERAL PRACTICE; HUMAN; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; RANDOMIZED CONTROLLED TRIAL; UNITED KINGDOM;

EID: 0033806648     PISSN: 10282327     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (24)

1. Moxonidine: A second-generation central antihypertensive agent
2. 1-imidazoline receptor agonist
3. 1-imidazoline receptors in the rostral ventrolateral medulla
4. Excess catecholamines and the metabolic syndrome: Should central imidazoline receptors be a therapeutic target?
5. Centrally acting antihypertensives: A renaissance of interest. Mechanisms and haemodynamics
6. Pharmacology and clinical use of moxonidine, a new centrally acting sympatholytic antihypertensive agent
7. Placebo-controlled comparison of the efficacy and tolerability of once-daily moxonidine and enalapril in mild to moderate essential hypertension
8. A double-blind comparison of moxonidine and atenolol in the management of patients with mild to moderate hypertension
9. The treatment of hypertensive patients with a calcium antagonist or moxonidine: A comparison
10. A double-blind crossover trial of moxonidine hydrochloride monohydrate (BF5895) and clonidine hydrochloride in hypertensive patients
11. Crossover comparison of moxonidine and clonidine in mild to moderate hypertension
12. Intraindividual comparison of moxonidine and prazosin in hypertensive patients
13. 1 receptor agonist moxonidine in patients with mild to moderate essential hypertension
14. 24-Hour blood pressure profiles in patients with mild-to-moderate hypertension: Moxonidine versus captopril
15. Aspects of tolerability of centrally acting antihypertensive drugs
16. Safety and tolerability of moxonidine in the treatment of hypertension
17. Moxonidine and hydrochlorothiazide in combination: A
18. Discontinuations of and changes in treatment after start of new courses of antihypertensive drugs: A study of a United Kingdom population
19. Continuation of initial antihypertensive medication after 1 year of therapy
20. Effect of intensive blood-pressure lowering and low-dose aspirin in patients with hypertension: Principal results of the Hypertension Optimised Treatment (HOT) randomised trial
21. Double-blind, parallel, comparative study on quality of life during treatment with amlodipine or enalapril in mild or moderate hypertensive patients: A multicentre study
22. Amlodipine: A reappraisal of its pharmacological properties and therapeutic use in cardiovascular disease
23. Treatment of hypertension by enalapril and hydrochlorothiazide separately and together: A multicenter study
24. Sixth report of the Joint National Committee on prevention, detection, evaluation, and treatment of high blood pressure