Expression and functional role of Co-stimulatory molecules in CD40+IL-4-stimulated B cells from atopic and non-atopic donors

Acta Dermato-Venereologica

Volumn 80, Issue 4, 2000, Pages 287-291

  Oberwalleney, G ^a   Henz, B M ^a   Worm, M ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

Atopic dermatitis; Co stimulatory molecules; IgE production

Indexed keywords

CD28 ANTIGEN; CD40 ANTIGEN; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; IMMUNOGLOBULIN E; INTERLEUKIN 4;

ANTIGEN EXPRESSION; ARTICLE; ATOPIC DERMATITIS; ATOPY; B LYMPHOCYTE ACTIVATION; CELL PROLIFERATION; CONTROLLED STUDY; HUMAN; HUMAN CELL; IMMUNOGLOBULIN PRODUCTION; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION;

EID: 0033805598     PISSN: 00015555     EISSN: None     Source Type: Journal    
DOI: 10.1080/000155500750012199     Document Type: Article

References (23)

1. Human B-cell proliferation and Ig secretion induced by recombinant CD40 ligand are modulated by soluble cytokines
2. Regulation of isotype switching
3. IL-4 treatment of small splenic B cells induces costimulatory molecules B7-1 and B7-2
4. Activated T cells induced expression of B7/BB1 normal or leukemic B cells through a CD40-dependent signal
5. The B7 and CD28 receptor families
6. Comparative analysis of B7-1 and B7-2 costimulatory ligands: Expression and function
7. Coexpression and functional cooperation of CTLA-4 and CD28 on activated T lymphocytes
8. Distinct roles for CD28 and cytotoxic T lymphocyte-associated molecule-4 receptors during T cell activation?
9. CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation
10. CD28 activation pathway regulates the production of multiple T cell-derived lymphokines/cytokines
11. Studies on the interdependence of gp39 and B7-expression and function during antigen-specific immune responses
12. CTLA-4 can function as a negative regulator of T cell activation
13. Loss of CTLA4 leads to massive lymphoproliferation and fatal multi-organ tissue destruction, revealing a critical negative immunoregulatory role of CTLA4
14. Diagnostic features of atopic dermatitis
15. Retinoic acid inhibits CD40+IL-4 mediated IgE-production in vitro
16. Functional properties of CD19+ B lymphocytes positively selected from buffy coats by immunomagnetic separation
17. Enhanced expression of B7-2 (CD86) in patients with atopic dermatitis: A potential role in the modulation of IgE synthesis
18. Upregulation of B7-2, but not B7-1, on B cells from patients with allergic asthma
19. CD86 (B7-2) antigen on B cells from atopic patients shows selective, antigen-specific upregulation
20. Functional CD86 (B7-2/B70) is predominantly expressed on Langerhans cells in atopic dermatitis
21. CD28 functions as an adhesion molecule and is involved in the regulation of human IgE synthesis
22. Absence of B7-dependent responses in CD28-deficient mice
23. Mice transgenic for a soluble form of murine CTLA-4 show enhanced expansion of antigen-specific CD4+ T cells and defective antibody production in vivo