Low serum insulin-like growth factor-binding protein- 1 is associated with an unfavourable cardiovascular risk profile in elderly men

Annals of Medicine

Volumn 32, Issue 6, 2000, Pages 424-428

  Harrela, M ^a   Koistinen, R ^a   Tuomilehto, J ^a   Nissinen, A ^a   Seppala, M ^a  

^a HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

Author keywords

Cardiovascular risk; Homeostasis model assessment; Insulin resistance; Insulin like growth factor binding protein 1; Insulin like growth factor binding protein 3; Insulin like growth factor I

Indexed keywords

GLUCOSE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INSULIN; SOMATOMEDIN BINDING PROTEIN 1; SOMATOMEDIN BINDING PROTEIN 3; TRIACYLGLYCEROL;

AGE; AGED; ARTICLE; BODY MASS; CARDIOVASCULAR RISK; COHORT ANALYSIS; CONTROLLED STUDY; DIET RESTRICTION; FLUOROMETRY; HOMEOSTASIS; HUMAN; INSULIN RELEASE; INSULIN RESISTANCE; INSULIN SENSITIVITY; LIOTHYRONINE BLOOD LEVEL; MAJOR CLINICAL STUDY; MALE; MEASUREMENT; MODEL; ORAL GLUCOSE TOLERANCE TEST; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; REGULATORY MECHANISM; RISK FACTOR;

EID: 0033804698     PISSN: 07853890     EISSN: None     Source Type: Journal    
DOI: 10.3109/07853890008995950     Document Type: Article

References (24)

1. Sex hormone binding globulin: A marker for hyperinsulinemia and/or insulin resistance?
2. Reduced insulin-like growth factor binding protein-1 (IGFBP-1) levels correlate with increased cardiovascular risk in non-insulin dependent diabetes mellitus (NIDDM)
3. Binding proteins for the insulin-like growth factors: Structure, regulation and function
4. An insulin-like growth factor binding protein enhances the biological response to IGF-I
5. Insulin regulates the serum levels of low molecular weight insulin-like growth factor binding protein
6. Portal insulin concentrations rather than insulin sensitivity regulate serum sex hormone-binding globulin and insulin-like growth factor binding protein-1 in vivo
7. The insulin-like growth factors: Their putative role in atherogenesis
8. Effects of insulin-like growth factor-I on glucose tolerance, insulin levels, and insulin secretion
9. Insulin-like growth factor-I improves glucose and lipid metabolism in type 2 diabetes mellitus
10. Direct demonstration of insulin-like growth factor-I-induced nitric oxide production by endothelial cells
11. Insulin-like growth factor I increases vascular smooth muscle nitric oxide production
12. Recombinant human IGF-I increases forearm blood flow
13. Characterization of induction of proto-onkogene c-myc and cellular growth in human vascular smooth muscle cells by insulin and IGF-I
14. Homeostasis model assessment: Insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man
15. Epidemiological studies related to coronary heart disease: Characteristics of men aged 40-59 in seven countries
16. Prevalence and change of cardiovascular risk factors among men born in 1900-1919: The finnish cohorts of the seven countries study
17. Enzymatic determination of cholesterol in HDL fractions prepared by polyanion precipitation
18. Placental protein 12(PP 12): Factors affecting levels in late pregnancy
19. Genetic and environmental components of interindividual variation in circulating levels of IGF-I, IGF-II, IGFBP-1, and IGFBP-3
20. Serum total IGF-I, free IGF-I, and IGFBP-1 levels in an elderly population: Relation to the cardiovascular risk factors and disease
21. Insulin-like factors I and II. Peptide, messenger ribonucleic acid and gene structures, serum and tissue concentrations
22. The growth hormone dependence of a somatomedin-binding protein in human serum
23. Clinical uses of insulin-like growth factor I