Differential host susceptibility to pulmonary infections with bacteria and fungi in mice deficient in myeloperoxidase

Journal of Infectious Diseases

Volumn 182, Issue 4, 2000, Pages 1276-1279

  Aratani, Yasuaki ^a   Kura, Fumiaki ^b   Watanabe, Haruo ^b   Akagawa, Hisayoshi ^b   Takano, Yukie ^b   Suzuki, Kazuo ^b   Maeda, Nobuyo ^c   Koyama, Hideki ^a  

^a YOKOHAMA CITY UNIVERSITY   (Japan)

^b NATIONAL INSTITUTE OF INFECTIOUS DISEASES   (Japan)

^c UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HYPOCHLOROUS ACID; MYELOPEROXIDASE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CANDIDA GLABRATA; CONTROLLED STUDY; CRYPTOCOCCUS NEOFORMANS; DRUG CYTOTOXICITY; ENZYME DEFECT; FEMALE; HOST SUSCEPTIBILITY; INFECTION RESISTANCE; LUNG INFECTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; STAPHYLOCOCCUS AUREUS; STREPTOCOCCUS PNEUMONIAE;

ANIMAL; ASPERGILLOSIS; ASPERGILLUS FUMIGATUS; BACTERIAL INFECTIONS; CANDIDIASIS; CRYPTOCOCCOSIS; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HOMOZYGOTE; KLEBSIELLA INFECTIONS; KLEBSIELLA PNEUMONIAE; LUNG DISEASES; LUNG DISEASES, FUNGAL; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PEROXIDASE; PNEUMONIA, PNEUMOCOCCAL; PSEUDOMONAS INFECTIONS; STAPHYLOCOCCAL INFECTIONS; SUPPORT, NON-U.S. GOV'T; TRICHOSPORON;

EID: 0033800733     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1086/315843     Document Type: Article

References (15)

1. Aspergillus and other fungi
2. Bacterial pneumonias
3. Myeloperoxidase
4. Myeloperoxidase deficiency
5. Myeloperoxidase deficiency: Prevalence and clinical significance
6. Severe impairment in early host defense against Candida albicans in mice deficient in myeloperoxidase
7. Damage to Candida albicans hyphae and pseudohyphae by the myeloperoxidase system and oxidative products of neutrophil metabolism in vitro
8. Bactericidal activity against Pseudomonas aeruginosa is acquired by cultured human monocyte-derived macrophages after uptake of myeloperoxidase
9. Mouse model of X-linked chronic granulomatous disease, an inherited defect in phagocyte superoxide production
10. Damage to Aspergillus fumigatus and Rhizopus oryzae hyphae by oxidative and nonoxidative microbicidal products of human neutrophils in vitro
11. Oxidative killing of Aspergillus fumigatus proceeds by parallel myeloperoxidase-dependent and -independent pathways
12. Candida glabrata: Review of epidemiology, pathogenesis, and clinical disease with comparison to C. albicans
13. Bactericidal mechanisms in rabbit alveolar macrophages: Evidence against peroxidase and hydrogen peroxide bactericidal mechanisms
14. Alveolar macrophages are required for protective pulmonary defenses in murine Klebsiella pneumonia: Elimination of alveolar macrophages increases neutrophil recruitment but decreases bacterial clearance and survival
15. Involvement of superoxide and myeloperoxidase in oxygen-dependent killing of Staphylococcus aureus by neutrophils