Effect of activated human protein C on disseminated intravascular coagulation induced by lipopolysaccharide in rats

Arzneimittel-Forschung/Drug Research

Volumn 50, Issue 9, 2000, Pages 809-815

  Aoki, Y ^a   Ota, M ^a   Katsuura, Y ^a   Komoriya, K ^a   Nakagaki, T ^a  

^a TEIJIN LTD   (Japan)

Author keywords

Activated protein C, effect on disseminated intravascular coagulation, rat, tissue damage; CTC 111; Lipopolysaccharide; Plasminogen activator inhibitor

Indexed keywords

ACTIVATED PROTEIN C; ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; BLOOD CLOTTING FACTOR 5A; BLOOD CLOTTING FACTOR 8A; CREATININE; CTC 111; ENZYME PRECURSOR; FIBRIN; FIBRINOGEN; HEPARIN; LIPOPOLYSACCHARIDE; PHENOBARBITAL; PLASMINOGEN ACTIVATOR INHIBITOR; SERINE PROTEINASE; THROMBIN; THROMBOMODULIN; UNCLASSIFIED DRUG; VITAMIN K GROUP;

ANIMAL EXPERIMENT; ANTICOAGULATION; ARTICLE; BLEEDING; BLOOD CLOTTING TIME; CONTROLLED STUDY; DISSEMINATED INTRAVASCULAR CLOTTING; DRUG ACTIVITY; DRUG EFFECT; FEMORAL VEIN; FIBRINOLYSIS; KIDNEY INJURY; LIVER INJURY; MALE; NONHUMAN; RAT; TISSUE INJURY; UREA NITROGEN BLOOD LEVEL;

EID: 0033799639     PISSN: 00044172     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-0031-1300293     Document Type: Article

References (22)

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13. Gerinnungsphysiologische schnellmethode zur bestimmung des fibrinogens
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15. Involvement of cytokine network in endotoxin syndrome
16. Increased plasma level of interleukin-6 in disseminated intravascular coagulation
17. Plasma level of IL-1β in disseminated intravascular coagulation
18. Plasma level of tumor necrosis factor in disseminated intravascular coagulation
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21. Activated protein C attenuates endotoxin-induced pulmonary vascular injury by inhibiting activated leukocytes in rats
22. Cytokines and plasminogen activator inhibitor-1 in posttrauma disseminated intravascular coagulation: Relationship to multiple organ dysfunction syndrome