CD59 protects rat kidney from complement mediated injury in collaboration with Crry

Kidney International

Volumn 58, Issue 4, 2000, Pages 1569-1579

  Watanabe, Midoriko ^a,b,c   Morita, Yoshiki ^a,b,c   Mizuno, Masashi ^a,b,c   Nishikawa, Kazuhiro ^a,b,c   Yuzawa, Yukio ^a,b,c   Hotta, Nigishi ^a,b,c   Morgan, B Paul ^a,b,c   Okada, Noriko ^a,b,c   Okada, Hidechika ^a,b,c   Matsuo, Seiichi ^a,b,c  

^a NAGOYA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b CARDIFF UNIVERSITY   (United Kingdom)

^c NAGOYA CITY UNIV MEDICAL SCHOOL   (Japan)

Author keywords

C3; Membrane attack complex; Peritubular capillaries; Renal protective agents; Tubulointerstitial injury

Indexed keywords

CD59 ANTIGEN; COMPLEMENT COMPONENT C3; COMPLEMENT MEMBRANE ATTACK COMPLEX;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COMPLEMENT ACTIVATION; COMPLEMENT SYSTEM; DOSE RESPONSE; IMMUNOHISTOCHEMISTRY; INTERSTITIAL NEPHRITIS; KIDNEY DISEASE; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN URINE LEVEL; RAT;

EID: 0033797265     PISSN: 00852538     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-1755.2000.00318.x     Document Type: Article

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2. Purification and characterization of membrane cofactor protein (gp45-70) which is a cofactor for cleavage of C3b and C4b
3. A novel membrane glycoprotein capable of inhibiting membrane attack by homologous complement
4. CD59, an Ly-6-like protein expressed in human lymphoid cells, regulates the action of the complement membrane attack complex on homologous cells
5. Isolation of a human erythrocyte membrane protein capable of inhibiting expression of homologous complement transmembrane channels
6. Isolation and characterization of a membrane protein from normal human erythrocytes that inhibits reactive lysis of the erythrocytes of paroxysmal nocturnal hemoglobinuria
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8. In vivo effects of monoclonal antibodies which functionally inhibit complement regulatory proteins in rats
9. Local inflammation caused by a monoclonal antibody that blocks the function of the function of the rat membrane inhibitor of C3 convertase
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11. Molecular Cloning of the rat complement regulatory protein, 5I2 antigen
12. Distinct receptor and regulatory properties of recombinant mouse complement receptor 1 (CR1) and Cry, the two genetic homologues of human CR1
13. Functional identification of transcription control sequences of the mouse Cry gene
14. Mouse Crry/p65 is a regulator of the alternative pathway of complement activation
15. Tissue distribution of complement regulatory membrane proteins in rats
16. Membrane attack complex of complement and 20 kDa homologous restriction factor (CD59) in myocardial infarction
17. High-level endothelial expression of human CD59 prolongs heart function in an ex vivo model of xenograft rejection
18. The effects of functional suppression of a membrane-bound complement regulatory protein, CD59, in the synovial tissue in rats
19. Isolation and characterization of a membrane protein from rat erythrocytes which inhibits lysis by the membrane attack complex of rat complement
20. Localization of the complement regulatory proteins in the normal human kidney
21. Tubulointerstitial injury induced in rats by a monoclonal antibody which inhibits function of a membrane inhibitor of complement
22. Role of a rat membrane inhibitor of complement in anti-basement membrane antibody-induced renal injury
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24. The use of avidin-biotin interaction in immunoenzymatic techniques
25. Urinary protein as measured with a pyrogallol red-molybdate complex, manually and in a Hitachi 726 automated analyzer
26. Experimental glomerulonephritis induced in rats by a lectin and its antibodies
27. Role of CD59 in experimental glomerulonephritis in rats
28. Retardation of fading and enhancement of intensity of immunofluorescence by p-phenylene-diamine
29. CD59 protects glomerular endothelial cells from immune-mediated thrombotic microangiopathy in rats
30. Biochemistry of C3 and related thioester proteins in infection and inflammation
31. Pathophysiology of chronic tubulointerstitial disease in rats: Interactions of dietary acid load, ammonia, and complement component C3
32. Molecular cloning and functional characterization of the rat analogue of human decay-accelerating factor (CD55)
33. Tissue distribution of the rat analogue of decay-accelerating factor
34. Inhibition of the alternative pathway of complement by glomerular chondroitin sulphate proteoglycan
35. Reduction in glomerular heparan sulfate correlates with complement deposition and albuminuria in active Heymann nephritis