Role of novel choline binding proteins in virulence of Streptococcus pneumoniae

Infection and Immunity

Volumn 68, Issue 10, 2000, Pages 5690-5695

  Gosink, K K ^a   Mann, E R ^a   Guglielmo, C ^a   Tuomanen, E I ^a   Masure, H R ^a  

^a ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL ENZYME; BINDING PROTEIN; CHOLINE; CHOLINE BINDING PROTEIN; CHOLINE BINDING PROTEIN D; CHOLINE BINDING PROTEIN E; CHOLINE BINDING PROTEIN G; HYDROLASE; LYTB PROTEIN; LYTC PROTEIN; MUTANT PROTEIN; PHOSPHORYLCHOLINE; SERINE PROTEINASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL CELL WALL; BACTERIAL COLONIZATION; BACTERIAL VIRULENCE; BACTERIUM ADHERENCE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FAMILY; RAT; SEPSIS; STREPTOCOCCUS PNEUMONIAE;

ANIMAL; BACTERIAL ADHESION; BACTERIAL PROTEINS; CARRIER PROTEINS; CELLS, CULTURED; CLONING, MOLECULAR; HUMAN; MOLECULAR SEQUENCE DATA; MUTAGENESIS, INSERTIONAL; NASOPHARYNX; PHOSPHORYLCHOLINE; PNEUMOCOCCAL INFECTIONS; RATS; STREPTOCOCCUS PNEUMONIAE; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; VIRULENCE;

EID: 0033796622     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.68.10.5690-5695.2000     Document Type: Article

References (36)

1. Sequence analysis of the gene for the glucan-binding protein of Streptococcus mutans Ingbritt
2. Nucleotide sequence of Clostridium difficile toxin B gene
3. Effect of insertional inactivation of the genes encoding pneumolysin and autolysin on the virulence of Streptococcus pneumoniae type 3
4. Interaction of the pneumococcal amidase with lipoteichoic acid and choline
5. The role of pneumolysin and autolysin in the pathology of pneumonia and septicemia in mice infected with a type 2 pneumucoccus
6. Molecular characterization of the Clostridium difficile toxin A gene
7. Sequence analysis of the glucosyltransferase A gene (gtfA) from Streptococcus mutans Ingbritt
8. Versatility of choline-binding domain
9. Nucleotide sequence and expression of the pneumococcal autolysin gene from its own promoter in Escherichia coli
10. LytB, a novel pneumococcal murein hydrolase essential for cell separation
11. The molecular characterization of the first autolytic lysozyme of Streptococcus pneumoniae reveals evolutionary mobile domain
12. Definition of a fundamental repeating unit in streptococcal glucosyltransferase glucan-binding regions and related sequences
13. Analysis of the Streptococcus downei gtfS gene, which specifies a glucosyltransferase that synthesizes soluble glucans
14. Evidence for high affinity binding-protein dependent transport systems in Gram-positive bacteria and in Mycoplasma
15. SpsA, a novel pneumococcal surface protein with specific binding to secretory immunoglobulin A and secretory component
16. A study of the genetic material determining an enzyme activity in pneumococcus
17. Peptide permeases modulate transformation in Streptococcus pneumoniae
18. Genetic identification of exported proteins in Streptococcus pneumoniae
19. Contribution of novel choline-binding proteins to adherence, colonization, and immunogenicity of Streptococcus pneumoniae
20. Molecular characterization of PcpA: A novel choline-binding protein of Streptococcus pneumoniae
21. Tracking the evolution of the bacterial choline binding domain: Molecular characterization of the Clostridium acetobutylicum NCIB 502 cspA gene
22. Structure of the cell wall anchor of surface proteins in Staphylococcus aureus
23. Bacterial meningitis in the United States
24. Sequence analysis of the gtfB gene from Streptococcus mutans
25. A 43-kilodalton pneumococcal surface protein PspA: Isolation, protective abilities, and structural analysis of the amino-terminal sequence
26. Choline in the cell wall of a bacterium: Novel type of polymer-linked choline in pneumococcus
27. Pneumococcal surface protein A inhibits complement activation by Streptococcus pneumoniae
28. The pathogenesis of pneumococcal infection: Correlation of clinical events with molecular mechanisms
29. Sequence analysis of the gtfC gene from Streptococcus mutans GS-5
30. Clostridium difficile toxin A carries a C-terminal repetitive structure homologous to the carbohydrate binding region of streptococcal glycosyltransferases
31. Identification, cloning and sequencing of the immunoglobulin AI protease gene of Streptococcus pneumoniae
32. The phosphorylcholine epitope undergoes phase variation on a 43-kilodalton protein in Pseudomonas aeruginosa and on pili of Neisseria meningitidis and Neisseria gonorrhoeae
33. Phosphorylcholine on the lipopolysaccharide of Haemophilus influenzae contributes to persistence in the respiratory tract and sensitivity to serum killing mediated by C-reactive protein
34. A family of clostridial and streptococcal ligand-binding proteins with conserved C-terminal repeat sequences
35. Novel surface attachment mechanism of the Streptococcus pneumoniae protein PspA