PBC: An infectious disease?

Gut

Volumn 47, Issue 4, 2000, Pages 586-588

  Haydon, G H ^a   Neuberger, J ^a  

^a QUEEN ELIZABETH HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL DNA; HLA ANTIGEN; MITOCHONDRION ANTIBODY; TIENILIC ACID;

AUTOIMMUNE DISEASE; BACTERIAL INFECTION; DISEASE TRANSMISSION; EPSTEIN BARR VIRUS; ESCHERICHIA COLI; FAMILIAL DISEASE; HEPATITIS C VIRUS; HUMAN; MIGRATION; MYCOBACTERIUM GORDONAE; PREVALENCE; PRIMARY BILIARY CIRRHOSIS; PRIORITY JOURNAL; SHORT SURVEY; VIRUS INFECTION;

AUTOIMMUNE DISEASES; BACTERIAL INFECTIONS; ENVIRONMENTAL EXPOSURE; HUMANS; LIVER CIRRHOSIS, BILIARY; MYCOBACTERIUM INFECTIONS; VIRUS DISEASES; WATER SUPPLY;

EID: 0033795241     PISSN: 00175749     EISSN: None     Source Type: Journal    
DOI: 10.1136/gut.47.4.586     Document Type: Short Survey

References (45)

1. 1 Czaja AJ. The variant forms of autoimmune hepatitis. Ann Intern Med 1996;125:588-98.
2. 2 Colombato LA, Alvarez F, Cote J, et al. Autoimmune cholangiopathy: the result of consecutive primary biliary cirrhosis and autoimmune hepatitis? Gastroenterology 1994;107:1838-43.
3. 3 Gershwin ME, Mackay IR, Sturgess A, et al. Identification and specificity of a cDNA encoding the 70kD mitochondrial antigen recognised in primary biliary cirrhosis. J Immunol 1987;138:3525-31.
4. 4 Surh CD, Danner DJ, Ahmad A, et al. Reactivity of PBC sera with a human fetal liver cDNA clone of branched chain alpha keto-acid dehydrogenase dihydrolipoamide acetyltransferase, the 53kD mitochondrial autoantigen. Hepatology 1989;9:63-8.
5. 5 Fussey SPM, Guest JR, James OFW, et al. Identification and analysis of the major M2 autoantigens in primary biliary cirrhosis. Proc Natl Acad Sci USA 1988;85:8654-8.
6. 6 Surh CD, Roche TE, Danner DJ, et al. Antimitochondrial autoantibodies in primary biliary cirrhosis recognise cross-reactive epitopes on protein X and dihydrolipoamide acetyltransferase of pyruvate dehydrogenase complex. Hepatology 1989;10:127-33.
7. 7 Fussey PM, Bassedine MF, Fittes D, et al. The E1 alpha and beta subunits of the pyruvate dehydrogenase complex are M2 "d" and M2 "e" autoantigens in primary biliary cirrhosis. Clin Sci 1989;77:365-8.
8. 8 Krams SM, Surh CD, Coppel RL, et al. Immunisation of experimental animals with dihydrolipoamide acetyltransferase, as a purified recombinant polypeptide, generates mitochondrial autoantibodies but not primary biliary cirrhosis. Hepatology 1989;9:411-16.
9. 9 Jones DE, Palmer JM, Yeaman S, et al. Breakdown of tolerance to pyruvate dehydrogenase complex in experimental autoimmune cholangitis: a mouse model of primary biliary cirrhosis. Hepatology 1999;30:65-70.
10. 10 Watson R, Angus PW, Dewar M, et al. Low prevalence of primary biliary cirrhosis in Victoria, Australia. Gut 1995;36:927-30.
11. 11 Anand AC, Elias E, Neuberger JM. End-stage primary biliary cirrhosis in a first generation migrant south Asian population. Eur J Gastroenterol Hepatol 1996;8:663-6.
12. 12 Triger DR. Primary biliary cirrhosis: is there an environmental contribution? J Gastroenterol Hepatol 1991;6:568-9.
13. 13 Chetwynd A, Diggle P, Jarner M, et al. Evidence for spatial variation in risk and of spatial clustering in PBC. Hepatology 1999;4(Pt 2):407A.
14. 14 Bach N, Schaffner F. Familial primary biliary cirrhosis. J Hepatol 1994;20:698-701.
15. 15 Brind AM, Bray GP, Portmann BC, et al. Prevalence and pattern of familial disease in primary biliary cirrhosis. Gut 1995;36:615-17.
16. 16 Gores GJ, Moore SB, Fisher LD, et al. Primary biliary cirrhosis associated with class II major histocompatibility complex antigens. Hepatology 1987;7: 889-92.
17. 17 Maeda T, Onoshi S, Saibara T, et al. HLA DR8 and primary biliary cirrhosis. Gastroenterology 1992;103:1118-19.
18. 18 Underhill JA, Donaldson PT, Doherty DG, et al. HLA DPB polymorphis in primary biliary cirrhosis. Hepatology 1995;21:959-62.
19. 19 Jones DE, Watt FE, Metcalf JV, et al. Familial primary biliary cirrhosis reassessed: a geographically-based population study. J Hepatol 1999;30: 402-7.
20. 20 Polson RJ, Portmann B, Neuberger J, et al. Evidence for disease recurrence after liver transplantation for primary biliary cirrhosis: clinical and histological follow up studies. Gastroenterology 1998;97:715-25.
21. 21 Neuberger J, Wallace L, Joplin R, et al. Hepatic distribution of E2 component of pyruvate dehydrogenase complex after transplantation. Hepatology 1995;22:798-801.
22. 22 Dimitrewski J, Hubscher SG, Mayer AD, et al. Recurrence of primary biliary cirrhosis in the liver allograft: the effect of immunosuppression. J Hepatol 1996;24:253-7.
23. 23 Sheiner PA, Schwartz ME, Mor E, et al. Severe or multiple rejection episodes are associated with early recurrence of hepatitis C after orthotopic liver transplantation. Hepatology 1995;2:30-4.
24. 24 Keogh A, Sadamoto T, Joplin R, et al. Expression of pyruvate dehydrogenase complex PDC-E2 on biliary epithelial cells induced by incubation with lymph nodes from primary biliary cirrhosis. Hepatology 1999;4(Pt 2):469A.
25. 25 Vilagut L, Vila J, Vinas O, et al. Cross reactivity of anti-Mycobacterium gordonae antibodies with the major mitochondrial autoantigens in primary biliary cirrhosis. J Hepatol 1994;21:673-77.
26. 26 O'Donohue J, McFarland B, Bomford A, et al. Antibodies to atypical Mycobacteriae in primary biliary cirrhosis. J Hepatol 1994:21:887-9.
27. 27 Jones DEJ, Palmer JM, Leon MP, et al. T cell responses to tuberculin purified protein derivative in primary biliary cirrhosis: evidence for defective T cell function. Gut 1997;40:277-83.
28. 28 O'Donohue J, Fidler H, Garcia-Barcelo M, et al. Mycobacterial DNA not detected in liver sections from patients with primary biliary cirrhosis. J Hepatol 1998;28:433-8.
29. 29 Lindenborn-Fotinos J, Baum H, Berg PA. Mitochondrial antigens in primary biliary cirrhosis; further characterisation of the M2 antigen by immunoblotting, revealing species and non-species determinants. Hepatology 1985;5:763-9.
30. 30 Stermerowicz R, Hopf U, Moller B, et al. Are mitochondrial antigens in primary biliary cirrhosis induced by (rough)-mutants of Enterobacteriaceae? Lancet 1988;2:1166-70.
31. 31 Hopf U, Moller B, Stermerowicz R, et al. Escherichia coli rough R mutants in the gut and lipid A in the liver from patients with primary biliary cirrhosis. Lancet 1989;2:1419-22.
32. 32 Burroughs AK, Rosenstein IJ, Epstein O, et al. Bacteriuria and primary biliary cirrhosis. Gut 1984;25:133-7.
33. 33 Butler P, Valle F, Hamilton-Miller JMT, et al. M2 mitochondrial antibodies and urinary rough mutant bacteria in patients with primary biliary cirrhosis and in patients with recurrent bacteriuria. J Hepatol 1992;17:483-8.
34. 34 Hopf U, Stermerowicz R. Can enterobacterial antigens induce a primary biliary cirrhosis? In: Meyer zum Buschenfelde KH, ed. Immunology and liver. Leicester: Kluwer Academic Press, 1993:447-58.
35. 35 Klein R, Wiebel M, Engelhart S, et al. Sera from patients with tuberculosis recognise the M2a-epitope (E2-subunit of pyruvate dehydrogenase) specific for primary biliary cirrhosis. Clin Exp Immunol ;92:308-16.
36. 36 Fussey SPM, Lindsay JG, Fuller C, et al. Autoantibodies in primary biliary cirrhosis: analysis of reactivity against eukaryotic and prokaryotic 2-oxo-acid dehydrogenase complexes. Hepatology 1991;13:467-74.
37. 37 Tanaka A, Prindiville TP, Gish R, et al. Are infectious agents involved in primary biliary cirrhosis? A PCR approach. J Hepatol 1999;31;664-71.
38. 38 Garry RF, Fermin CD, Hart DJ, et al. Detection of a human intracisternal A-type retroviral particle antigenically related to HIV. Science 1990;250: 1127-9.
39. 39 Mason AL, Xu L, Guo L, et al. Detection of retroviral antibodies in primary biliary cirrhosis and other idiopathic biliary disorders. Lancet 1998;351: 1620-4.
40. 40 Lunel F, Musset I, Cacoub P, et al. Cryoglobulinaemia in chronic liver diseases: role of hepatitis C virus and liver damage. Gastroenterology 1994; 106:1291-300.
41. 41 Roffi L, Mels GC, Antonelli G, et al. Breakthrough during recombinant interferon alpha therapy in patients with chronic hepatitis C virus infection: prevalence, aetiology and management. Hepatology 1995;21:645-9.
42. 42 Molberg O, Mcadam SN, Korner R, et al. Tissue transglutaminase selectively modifies gliadin peptides that are recognised by gut-derived T cells in celiac disease. Nat Med 1998;4:713-17.
43. 43 Ellis TM, Atkinson MA. Early infant diets and insulin-dependent diabetes. Lancet 1996:347:1464-5.
44. 44 Horwitz MS, Sarvetnick N. Viruses, host responses, and immunity. Immunol Rev 1999;169:241-53.
45. 45 Shimoda S, Nakamura M, Ishishibashi H. HLA DRB4 0101-restricted immunodominant T-cell autoepitope of pyruvate dehydrogenase complex in primary biliary cirrhosis: evidence of molecular mimicry in human autoimmune disease. J Exp Med 1995;181:1835-45.