Influence of longterm CPAP therapy on CO2 drive in patients with obstructive sleep apnea

Respiration Physiology

Volumn 123, Issue 1-2, 2000, Pages 121-130

  Verbraecken, J ^a   Willemen, M ^b   De Cock, W ^b   Wittesaele, W ^b   Govaert, K ^b   Van De Heyning, P ^b   De Backer, W ^b  

^a MAASTRICHT UNIVERSITY   (Netherlands)

^b UNIVERSITY OF ANTWERP   (Belgium)

Author keywords

CO2, hypercapnic ventilatory response; Control of breathing, hypercapnic ventilatory response; Disease, obstructive sleep apnea; Mammals, humans; Sleep, apnea, obstructive; Upper airways, obstructive sleep apnea; Ventilation, artificial, CPAP, long term

Indexed keywords

CARBON DIOXIDE;

ADULT; ARTICLE; BLOOD GAS ANALYSIS; CARBON DIOXIDE TENSION; CONTROLLED STUDY; FEMALE; GAS EXCHANGE; HUMAN; MAJOR CLINICAL STUDY; MALE; OXYGEN TENSION; POSITIVE END EXPIRATORY PRESSURE; PRIORITY JOURNAL; RESPIRATION CONTROL; SLEEP APNEA SYNDROME; WAKEFULNESS;

BLOOD GAS ANALYSIS; CARBON DIOXIDE; ELECTROENCEPHALOGRAPHY; FEMALE; HUMAN; MALE; MIDDLE AGE; PULMONARY GAS EXCHANGE; RESPIRATION; RESPIRATION, ARTIFICIAL; RESPIRATORY FUNCTION TESTS; SLEEP APNEA, OBSTRUCTIVE; SLEEP STAGES;

EID: 0033795158     PISSN: 00345687     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0034-5687(00)00140-7     Document Type: Article

References (29)

1. 2 with long-term CPAP therapy for obstructive sleep apnea. Am. Rev. Respir. Dis. 135:1987;144-147.
2. Chaouat A., Weitzenblum E., Krieger J., Oswald M., Kessler R. Pulmonary hemodynamics in the obstructive sleep apnea syndrome. Results in 220 consecutive patients. Chest. 109:1996;380-386.
3. 2 desaturation and daytime pulmonary haemodynamics in COPD patients with mild hypoxaemia. Eur. Respir. J. 10:1997;1730-1735.
4. Coates A.L., Peslin R., Rodenstein D., Stocks J. Measurement of lung volumes by plethysmography. Eur. Respir. J. 10:1997;1415-1427.
5. Douglas F.G., Chong P.Y. Influence of obesity on peripheral airways patency. J. Appl. Physiol. 33:1972;559-563.
6. Fenn O., Rahn H., Otis A.B. A theoretical study of the composition of alveolar air. Am. J. Physiol. 146:1946;637-641.
7. Gold A.R., Schwartz A.R., Bleecker E.R., Smith P.L. The effect of chronic nocturnal oxygen administration upon sleep apnea. Am. Rev. Respir. Dis. 134:1986;925-929.
8. 2 after tracheostomy in obstructive sleep apnea syndrome. Am. Rev. Respir. Dis. 126:1982;14-20.
9. Hedner J., Darpo B., Ejnell H., Calson J., Caidahl K. Reduction in sympathetic activity after long-term CPAP treatment in sleep apnoea: cardiovascular implications. Eur. Respir. J. 8:1995;222-229.
10. Lampert E., Schnededecker B., Krieger J. Ventilatory and mouth occlusion pressure responses to progressive normoxic hypercapnia in obstructive sleep apnea syndrome. Results before and after longterm treatment with nasal CPAP. Sleep. 1990:1990;206-208.
11. Leech J.A., Onal E., Lopata M. Nasal CPAP continues to improve sleep-disordered breathing and daytime oxygenation over long-term follow-up of occlusive sleep apnea syndrome. Chest. 102:1992;1651-1655.
12. Nishimura M., Yamamoto M., Yoshioka A., Akiyama Y., Kishi F., Kawakami Y. Longitudinal analyses of respiratory chemosensitivity in normal subjects. Am. Rev. Respir. Dis. 143:1991;1278-1281.
13. Oku Y., Saidel G.M., Cherniack N.S., Altose M.D. Effects of willful ventilatory control on respiratory sensation during hypercapnia. Respiration. 63:1996;137-143.
14. Osanai S., Akiba Y., Fujiuchi S., Nakano H., Matsumoto H., Ohsaki Y., Kikuchi K. Depression of peripheral chemosensitivity by a dopaminergic mechanism in patients with obstructive sleep apnoea syndrome. Eur. Respir. J. 13:1999;418-423.
15. 2 with or without inspiratory load after CPAP therapy for obstructive sleep apnoea syndrome (OSAS). Eur. Respir. J. 4:1991;585s.
16. Quanjer P.H., Tammeling G.J., Cotes J.E., Pedersen O.F., Peslin R., Yernault J.C. Lung volumes and forced ventilatory flows. Report working party standardization of lung function tests European Community for Steel and Coal. Eur. Respir. J. 6:1993;5-40.
17. Radwan L., Maszczyk Z., Koziorowski A., Koziej M., Cieslicki J., Sliwinski P., Zielinski J. Control of breathing in obstructive sleep apnoea and in patients with the overlap syndrome. Eur. Respir. J. 8:1995;542-545.
18. Read D.J.C. A clinical method for assessing the ventilatory response to carbon dioxide. Aust. Ann. Med. 16:1967;20-32.
19. Rechtschaffen, A., Kales, A., 1968. A manual of standardised terminology, techniques and scoring for sleep stages of human subjects. Brain Information Service/Brain Research Institute, University of California (UCLA), Los Angeles, CA.
20. Redline S., Leitner J., Arnold J., Tishler P., Altose M. Ventilatory-control abnormalities in familial sleep apnea. Am. J. Respir. Crit. Care Med. 156:1997;155-160.
21. Rigg J.R.A., Inman E.M., Saunders N.A., Leeder S.R., Jones N.L. Interaction of mental factors with hypercapnic ventilatory drive in man. Clin. Sci. Mol. Med. 52:1977;269-275.
22. Rochester D. Current concept in the pathogenesis of the obesity-hypoventilation syndrome. Am. J. Med. 57:1974;402-420.
23. Sajkov D., Wang T., Saunders N.A., Bune A.J., Neill A.M., McEvoy R.D. Daytime pulmonary hemodynamics in patients with obstructive sleep apnea without lung disease. Am. J. Respir. Crit. Care Med. 159:1999;1518-1526.
24. Sforza E., Krieger J., Weitzenblum E., Apprill M., Lampert E., Ratamaharo J. Long-term effects of treatment with nasal continuous positive airway pressure on daytime lung function and pulmonary hemodynamics in patients with obstructive sleep apnea. Am. Rev. Respir. Dis. 141:1990;866-870.
25. Sforza E., Boudewijns A., Schnedecker B., Zamagni M., Krieger J. Role of chemosensitivity in intrathoracic pressure changes during obstructive sleep apnea. Am. J. Respir. Crit. Care Med. 154:1996;1741-1747.
26. Sullivan C.E., Issa F.G., Berthon-Jones M., Eves L. Reversal of obstructive sleep apnoea by continuous positive airway pressure applied through the nares. Lancet. 1:1981;862-865.
27. 2 drive in patients with obstructive sleep apnea and effect of CPAP. Respir. Physiol. 101:1995;279-287.
28. 2 drive and characteristics of apneas in obstructive and central sleep apnea. Respir. Physiol. 114:1998;185-194.
29. Weil J.V., Byrne-Quin F., Sodal I.E., Filley G.F., Grover R.F. Acquired attenuation of chemoreceptor function in chronically hypoxic man at high altitude. J. Clin. Invest. 50:1971;186-195.