Testing of individual blood donations for HCV RNA reduces the residual risk of transfusion-transmitted HCV infection

Transfusion

Volumn 40, Issue 10, 2000, Pages 1192-1197

  Legler, Tobias J ^a   Riggert, Joachim ^a   Simson, Georg ^a   Wolf, Cornelia ^a   Humpe, Andreas ^a   Munzel, Ullrich ^a   Uy, Angela ^a   Köhler, Michael ^a   Heermann, Klaus Hinrich ^a  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

HEPATITIS C ANTIBODY; VIRUS RNA;

ACCURACY; ARTICLE; BLOOD DONOR; BLOOD SAMPLING; BLOOD TRANSFUSION; CLINICAL TRIAL; COST EFFECTIVENESS ANALYSIS; HEPATITIS C; HUMAN; INFECTION RISK; POLYMERASE CHAIN REACTION; REFERENCE VALUE; SCREENING TEST; VIRUS LOAD;

BLOOD DONORS; BLOOD TRANSFUSION; FALSE POSITIVE REACTIONS; HEPACIVIRUS; HEPATITIS C; HUMANS; REPRODUCIBILITY OF RESULTS; RISK FACTORS; RNA, VIRAL; SENSITIVITY AND SPECIFICITY;

EID: 0033792738     PISSN: 00411132     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1537-2995.2000.40101192.x     Document Type: Article

References (20)

1. Hepatitis C
2. The risk of transfusion-transmitted viral infections. The Retrovirus Epidemiology Donor Study
3. Risk of hepatitis C virus (HCV) transmission by anti-HCV-negative blood components in Austria and Germany
4. Mini-pool screening by nucleic acid testing for hepatitis B virus, hepatitis C virus, and HIV: Preliminary results
5. Feasibility and efficacy of routine PCR screening of blood donations for hepatitis C virus, hepatitis B virus, and HIV-1 in a blood-bank setting
6. Genomic screening for blood-borne viruses in transfusion settings
7. High-throughput extraction, amplification, and detection (HEAD) of HCV-RNA in individual blood donations
8. Low levels of hepatitis C virus RNA in serum, plasma, and peripheral blood mononuclear cells of injecting drug users during long anti-body-undetectable periods before seroconversion
9. International collaborative study on the second EUROHEP HCV RNA reference panel
10. COBAS AMPLICOR: Fully automated RNA and DNA amplification and detection system for routine diagnostic PCR
11. Performance of the automated COBAS AMPLICOR system for the detection of hepatitis C virus RNA
12. Evaluation of automated COBAS AMPLICOR PCR system for detection of several infectious agents and its impact on laboratory management
13. Routes of infection, viremia, and liver disease in blood donors found to have hepatitis C virus infection
14. Blood donors who are repeatedly reactive for hepatitis C virus on enzyme immunoassay and positive on recombinant immunoblot assay: Evidence of failure to identify some risk factors
15. Study by the Professional Organization of German Transfusion Physicians on epidemiology of HIV and hepatitis infections in blood donors
16. Collaborative study to assess the suitability of an HCV RNA reference sample for detection of an HCV BNA in plasma pools by PCR
17. Mini-Pool testing by the polymerase chain reaction for viral nucleic acids: HCV concentration efforts
18. Equilibrium centrifugation studies of hepatitis C virus: Evidence for circulating immune complexes
19. Hepatitis C virus particle detected by immunoelectron microscopic study