Development of enzyme-linked immunosorbent assays for toxic larkspur (Delphinium spp.) alkaloids

Journal of Agricultural and Food Chemistry

Volumn 48, Issue 10, 2000, Pages 4520-4528

  Lee, S T ^a   Schoch, T K ^b   Gardner, D R ^a   Stegelmeier, B L ^a  

^a AGRICULTURAL RESEARCH SERVICE   (United States)

^b WESTERN REGIONAL RESEARCH CENTER   (United States)

Author keywords

Delphinium; Enzyme linked immunoassay; Larkspur; Norditerpenoid alkaloids

Indexed keywords

ALKALOID; HAPTEN; MEDICINAL PLANT; METHYLLYCACONITINE; N (METHYLSUCCINIMIDO)ANTHRANOYLLYCOCTONINE; PLANT TOXIN; POLYCLONAL ANTIBODY; UNCLASSIFIED DRUG;

AGRICULTURE; ANIMAL; ANIMAL TISSUE; ARTICLE; BRAIN LEVEL; BRAIN TISSUE; CATTLE; COMPETITIVE INHIBITION; CONTROLLED STUDY; COW; CROSS REACTION; ENZYME LINKED IMMUNOSORBENT ASSAY; NONHUMAN; PHYTOTOXICITY; QUANTITATIVE ASSAY;

ALKALOIDS; ANIMALS; BRAIN CHEMISTRY; CATTLE; CROSS REACTIONS; ENZYME-LINKED IMMUNOSORBENT ASSAY; HAPTENS; PLANTS, MEDICINAL;

ANIMALIA; BOS TAURUS; BOVINAE; DELPHINIUM;

EID: 0033792487     PISSN: 00218561     EISSN: None     Source Type: Journal    
DOI: 10.1021/jf000600h     Document Type: Article

References (27)

1. The toxicology and pharmacology of diterpenoid alkaloids
2. A competitive enzyme-linked immunosorbent assay (ELISA) to detect retronecine and monocrotaline in vitro
3. 3, 3', 5, 5'-Tetramethylbenzidine as an ames test negative chromogen for horseradish peroxidase in enzyme-immunoassay
4. Tall larkspur and cattle on high mountain ranges
5. Quantitative analysis of norditerpenoid alkaloids in larkspur (Delphimium spp.) by Fourier transform infrared spectroscopy
6. Analysis of toxic norditerpenoid alkaloids in delphinium species by electrospray, atmospheric pressure chemical ionization, and sequential tandem mass spectrometry
7. Three new toxic norditerpenoid alkaloids from the low larkspur Delphinium nuttallianum
8. Polyclonal antibodies to domoic acid, and their use in immunoassays for domoic acid in seawater and shellfish
9. Development and application of an enzyme-linked immunosorbent assay for lupin alkaloids
10. Delphinium alkaloids as inhibitors of a-bungarotoxin binding in rat and insect neural membranes
11. A competitive enzyme linked immunoassay for the pyrrolizidine alkaloids of the senecionine type
12. Normal phase liquid chromatographic analysis of toxic norditerpenoid alkaloids
13. Larkspur chemistry: Toxic alkaloids in tall larkspurs
14. Toxicity and chemical phenology of norditerpenoid alkaloids in the tall larkspurs (Delphinium species)
15. Structure-activity relationships of norditerpenoid alkaloids occurring in toxic larkspur (Delphinium species)
16. Clinical signs and studies of the site of action of purified larkspur alkaloid, methyllycaconitine, administered parenterally to calves
17. Larkspur: Economic considerations
18. Tall larkspur poisoning in cattle and sheep
19. Poisonous properties of larkspurs (Delphinium spp.)
20. Diterpene alkaloids from Aconitum, Delphinium, and Garrya species
21. Plant-animal interactions in larkspur poisoning in cattle
22. Development of class-specific competitive enzyme-linked immunosorbent assay for the detection of pyrrolizidine alkaloids in vitro
23. Enzyme-linked immunosorbent assay detection of pyrrolizidine alkaloids: Immunogens based on quaternary pyrrolizidium salts
24. Developments of immunoassays for tyramine and tryptamine toxins of Phalaris aquatica L
25. A sensitive technique for the detection of the α7 neuronal nicotinic acetylcholine receptor antagonist, methyllycaconitine, in rat plasma and brain
26. Five poisonous range plants - When and why they are dangerous
27. Improving methods for conjugating selected mycotoxins to carrier proteins and dextran for immunoassays