Synthetic protein design: Construction of a four-stranded β-sheet structure and evaluation of its integrity in methanol-water systems

Journal of Peptide Research

Volumn 56, Issue 5, 2000, Pages 307-317

  Das, C ^a   Balaram, P ^a   Nayak, V ^a   Raghothama, S ^a  

^a INDIAN INSTITUTE OF SCIENCE   (India)

Author keywords

Conformational analysis; Designed sheet motif; NMR; Protein design; Synthetic peptide

Indexed keywords

METHANOL; WATER;

AMINO ACID SEQUENCE; ARTICLE; CIRCULAR DICHROISM; HYDROGEN BOND; NUCLEAR OVERHAUSER EFFECT; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN STRUCTURE; PROTEIN SYNTHESIS; STRUCTURE ANALYSIS;

AMINO ACID SEQUENCE; CIRCULAR DICHROISM; HYDROGEN BONDING; MAGNETIC RESONANCE SPECTROSCOPY; METHANOL; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PEPTIDES; PROTEIN ENGINEERING; PROTEIN FOLDING; PROTEIN STRUCTURE, SECONDARY; TEMPERATURE; WATER;

EID: 0033791957     PISSN: 1397002X     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1399-3011.2000.00775.x     Document Type: Article

References (65)

1. De novo design and structural characterization of proteins and metalloproteins
2. Native-like and structurally characterized designed α-helical bundles
3. Looking at proteins: Repesentations, folding, packing and design
4. Beta-doublet: De novo design, synthesis, and characterization of a β-sandwich protein
5. Construction and design of β-sheets
6. Engineering of betabellin 14D: Disulfide-induced folding of a β-sheet protein
7. 2D, a nativelike de novo designed protein
8. Design of a monomeric 23-residue polypeptide with defined tertiary structure
9. De novo protein design: Fully automated sequence selection
10. Deciphering rules of helix stability
11. Solution structure and dynamics of a de novo designed three-helix bundle protein
12. A native-like three-α-helix bundle protein from structure-based redesign: A novel maquette scaffold
13. Structure and function of an aromatic ensemble that restricts the dynamics of the hydrophobic core of designed helix-loop-helix dimer
14. A designed four helix bundle protein with native-like structure
15. Stereochemical requirements for β-hairpin formation: Model studies with four-residue peptides and depsipeptides
16. Insights on β-hairpin stability in aqueous solution from peptides with enforced type I' and type II' β-turns
17. A designed β-hairpin peptide
18. A designed β-hairpin peptide in crystals
19. β-Hairpin nucleation by Pro-Gly β-turns. Comparison of D-Pro-Gly and L-Pro-Gly sequences in an apolar octapeptide
20. De novo design and structural analysis of a model β-hairpin system
21. Conformational investigation of designed short linear peptides able to fold into β-hairpin structures in aqueous solution
22. Cross-strand side-chain interactions versus turn conformation in β-hairpins
23. Origin of β-hairpin stability in solution: Structural and thermodynamic analysis of the folding of a model peptide supports hydrophobic stabilization in water
24. Design of a 20-amino acid three-stranded beta-sheet protein
25. Use of a designed triple-stranded antiparallel β-sheet to probe β-sheet cooperativity in aqueous solution
26. Cooperative interaction between the three strands of a designed antiparallel β-sheet
27. A designed three-stranded β-sheet peptide as a multiple β-hairpin model
28. De novo design of a monomeric three-stranded antiparallel β-sheet
29. β-Hairpin families in globular proteins
30. Conformation of β-hairpins in protein structures
31. β-Hairpins in proteins revisited: Lessons for de novo design
32. IUPAC-IUB Commission on Biochemical Nomenclature
33. The anatomy and taxonomy of protein structures
34. Conformational characteristics of aspariginyl residues in proteins
35. Rules for antiparallel β-sheet design: D-Pro-Gly is superior to L-Asn-Gly for β-hairpin nucleation
36. An analysis of sidcchain interactions and pair correlations within antiparallel beta-sheets: The differences backbone hydrogen-boned and non-hydrogen-bonded residue pairs
37. A four stranded β-sheet structure in a designed, synthetic polypeptide
38. Thermodynamic beta-sheet propensities measured using a zinc-finger host peptide
39. A thermodynamic scale of the beta-sheet forming tendencies of the amino acids
40. Measurement of the beta-sheet-forming propensities of the amino acids
41. NMR chemical shifts of common laboratory solvents as trace impurities
42. Multiple quantum filters for elucidating NMR coupling networks
43. Coherence transfer by isotropic mixing: Application to proton correlation spectroscopy
44. A two-dimensional nuclear Overhauser enhancement (2D NOE) experiment for the elucidation of complete proton-proton cross-relaxation networks in biological macromolecules
45. Practical aspects of two-dimensional transverse NOE spectroscopy
46. Structure determination of a tetrasaccharide: Transient nuclear Overhauser effects in the rotating frame
47. Torsion angle dynamics for NMR structure calculation with the new program DYANA
48. MOLMOL: A program for display and analysis of macromolecular structures
49. 3J(HNα), in a globular protein
50. Hydrogen exchange and structural dynamics of proteins and nucleic acids
51. Polypeptide restricted backbone conformation
52. The design of linear peptides that fold as monomeric β-sheet structures
53. The chemical shift index: A fast and simple method for the assignment of protein secondary structure through NMR spectroscopy
54. Relationship between nuclear magnetic resonance chemical shift and protein secondary structure
55. Tyrosine, phenylalanine, and disulfide contributions to the circular dichroism of proteins: Circular dichroism spectra of wildtype and mutant bovine pancreatic trypsin inhibitor
56. Aromatic side-chain contribution to far-ultraviolet circular dichroism of helical peptides and its effect on measurement of helix propensities
57. Vibrational circular dichroism of β-hairpin peptides
58. De novo design, expression, and characterization of felix: A four-helix bundle protein of native-like sequence
59. Economy in protein design: Evolution of a metal-independent ββα motif based on the zinc finger domains
60. Principles determining the structure of β-sheet barrels in protens. II. The observed structures
61. Porins: General to specific, native to engineered passive pores
62. β-Barrel proteins from bacterial outer membranes: Structure, function and refolding