A novel role of differentiation-inducing factor-1 in Dictyostelium development, assessed by the restoration of a developmental defect in a mutant lacking mitogen-activated protein kinase ERK2

Development Growth and Differentiation

Volumn 42, Issue 5, 2000, Pages 531-538

  Kuwayama, Hidekazu ^a   Oyama, Masakazu ^b   Kubohara, Yuzuru ^c   Maeda, Mineko ^a  

^a OSAKA UNIVERSITY   (Japan)

^b UNIVERSITY OF HYOGO   (Japan)

^c GUNMA UNIVERSITY   (Japan)

Author keywords

Cyclic adenosine monophosphate; Dictyostelium; DIF 1; Extracellular signal regulated kinase 2; Mitogen activated protein kinase; Protein kinase A; Signal transduction

Indexed keywords

ADENYLATE CYCLASE; COMPLEMENTARY DNA; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP RECEPTOR; DIFFERENTIATION INDUCING FACTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE;

ARTICLE; CELL DENSITY; CELL DIFFERENTIATION; CONTROLLED STUDY; DEVELOPMENTAL DISORDER; DICTYOSTELIUM DISCOIDEUM; ENZYME ACTIVITY; NONHUMAN; NORTHERN BLOTTING;

ANIMALS; BLOTTING, NORTHERN; CYCLIC AMP; DICTYOSTELIUM; HEXANONES; MITOGEN-ACTIVATED PROTEIN KINASE 1; MORPHOGENESIS; MUTATION;

DICTYOSTELIUM; DICTYOSTELIUM DISCOIDEUM; EUKARYOTA; GASTROPODA;

EID: 0033788189     PISSN: 00121592     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1440-169X.2000.00537.x     Document Type: Article

References (33)

1. The Dictyostelium mitogen-activated protein kinase ERK2 is regulated by ras and cAMP-dependent protein kinase (PKA) and mediates PKA function
2. A Dictyostelium mutant with defective aggregate size determination
3. Developmental regulation of a stalk cell differentiation-inducing factor in Dictyostelium discoideum
4. A novel cytosolic regulator, Pianissimo, is required for chemoattractant receptor and G protein-mediated activation of the 12 transmembrane domain adenylyl cyclase in Dictyostelium
5. LagC is required for cell-cell interactions that are essential for cell-type differentiation in Dictyostelium
6. The Dictyostelium MAP kinase ERK2 regulates multiple, independent developmental pathways
7. A myb-related protein required for culmination in Dictyostelium
8. Cell cycle-dependent regulation of early developmental genes
9. CRAC, a cytosolic protein containing a pleckstrin homology domain, is required for receptor and G-protein mediated activation of adenylyl cyclase in Dictyostelium
10. DIF Signalling
11. Purification of stalk-cell-inducing morphogens from Dictyostelium discoideum
12. A chemoattractant receptor controls development in Dictyostelium discoideum
13. Dictyostelium mutants lacking DIF, a putative morphogen
14. Regulation and function of G alpha protein subunits in Dictyostelium
15. A G-protein beta-subunit is essential for Dictyostelium development
16. Seven helix chemoattractant receptors transiently stimulate mitogen-activated protein kinase in Dictyostelium. Role of heterotrimeric G proteins
17. A diffusible factor involved in MAP-kinase ERK-2-regulated development of Dictyostelium
18. Role of cAMP-dependent protein kinase in controlling aggregation and post-aggregative development in Dictyostelium
19. A developmentally regulated, putative serine/threonine protein kinase is essential for development in Dictyostelium
20. Differentiation-inducing factor from the slime mould Dictyostelium discoideum and its analogues. Synthesis, structure and biological activity
21. The Dictyostelium developmental cDNA project: Generation and analysis of expressed sequence tags from the first-finger stage of development
22. Chemical structure of the morphogen differentiation inducing factor from Dictyostelium discoideum
23. Differentiation-inducing-factor dechlorinase, a novel cytosolic dechlorinating enzyme from Dictyostelium discoideum
24. Complete sequence and transcript regulation of a cell adhesion protein from aggregating Dictyostelium cells
25. A novel Myb homolog initiates Dictyostelium development by induction of adenylyl cyclase expression
26. Role of a guanine nucleotide binding protein, G alpha 2, in regulation of adenylate cyclase in Dictyostelium discoideum
27. Structurally distinct and stage-specific adenylyl cyclase genes play different roles in Dictyostelium development
28. A MAP-kinase necessary for receptor-mediated activation of adenylyl cyclase in Dictyostelium
29. A multidrug resistance transporter serine protease gene is required for prestalk specialization in Dictyostelium
30. Starvation promotes Dictyostelium development by relieving PufA inhibition of PKA translation through the YakA kinase pathway
31. YakA, a protein kinase required for the transition from growth to development in Dictyostelium
32. Gene targeting of the aggregation stage cAMP receptor cAR1 in Dictyostelium
33. New roles for DIF? Effects on early development in Dictyostelium