Effect of compression force on the crystal properties of erythromycin acistrate tablets

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 50, Issue 3, 2000, Pages 365-371

  Riippi, Merja ^a   Tanninen, Veli Pekka ^a   Yliruusi, Jouko ^b  

^a ORION CORPORATION   (Finland)

^b UNIVERSITY OF HELSINKI   (Finland)

Author keywords

Compression force; Crystal properties; Crystallite size; Erythromycin acistrate; Full width at half maximum; Integral breadth; Preferred orientation; Tablet; X ray powder diffraction

Indexed keywords

ERYTHROMYCIN ACISTRATE;

ARTICLE; CRYSTAL STRUCTURE; DRUG MANUFACTURE; POWDER; SCANNING ELECTRON MICROSCOPY; TABLET COMPRESSION; X RAY DIFFRACTION;

CHEMISTRY, PHARMACEUTICAL; COMPRESSIVE STRENGTH; CRYSTALLIZATION; ERYTHROMYCIN; MICROSCOPY, ELECTRON, SCANNING; PARTICLE SIZE; POWDERS; PRODRUGS; SUPPORT, NON-U.S. GOV'T; TABLETS; X-RAY DIFFRACTION;

EID: 0033787394     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0939-6411(00)00116-8     Document Type: Article

References (19)

1. Solid-state properties of powders in the formulation and processing of solid dosage forms
2. Modification of starting materials to improve tabletting properties
3. The compaction properties of nitrofurantoin samples crystallised from different solvents
4. Formation and compression characteristics of prismatic polyhedral and thin plate-like crystals of paracetamol
5. Effects of grinding and compression on crystal structure of anhydrous caffeine
6. Physicochemical characterization of naproxen and griseofulvin crystals by X-ray powder diffraction
7. Untersuchungen uber die Textur und die Eigenschaften von Sulfaethidol-Tabletten
8. Preferred orientation of crystallites in tablets II. Evaluation of preferred orientation of crystallites by X-ray powder diffractometry
9. Preferred orientation of crystallites in tablets III. Variations of crystallinity and crystallite size of pharmaceuticals with compression
10. Preferred orientation of crystallites in tablets. V. Pattern-fitting procedure for the determination of strength of preferred orientation of crystallites
11. Pattern fitting procedure for the characterization of crystals and/or crystallites in tablets
12. The effect of compression force on surface structure, crushing strength, friability and disintegration time of erythromycin acistrate tablets
13. Twice daily dosing of erythromycin acistrate in the treatment of acute bronchitis and pneumonia
14. Effect of food on absorption and hydrolysis of erythromycin acistrate
15. New parameters derived from tablet compression curves. Part I. Force-time curve
16. New parameters derived from tablet compression curves. Part II. Force-displacement curve
17. Effect of co-solvent on water content and physical properties of acetaminophen crystallised from aqueous solutions