Sec61p is the main ribosome receptor in the endoplasmic reticulum of saccharomyces cerevisiae

Biological Chemistry

Volumn 381, Issue 9-10, 2000, Pages 1025-1029

  Prinz, A ^a   Hartmann, E ^a   Kalies, K U ^a  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

Author keywords

Co translational translocation; Ribosome binding; Sec61p; Ssh1p; Yeast

Indexed keywords

FUNGAL PROTEIN; MEMBRANE RECEPTOR; POLYPEPTIDE; RIBOSOME PROTEIN; SEC61 PROTEIN; SECRETORY PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; BINDING SITE; BIOCHEMISTRY; COMPLEX FORMATION; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; FUNGAL GENETICS; FUNGUS GROWTH; MAMMAL CELL; MEMBRANE TRANSPORT; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN TRANSPORT; RIBOSOME; SACCHAROMYCES CEREVISIAE; SEQUENCE HOMOLOGY; YEAST;

FUNGI; MAMMALIA; SACCHAROMYCES CEREVISIAE;

EID: 0033787091     PISSN: 14316730     EISSN: None     Source Type: Journal    
DOI: 10.1515/BC.2000.126     Document Type: Article

References (17)

1. Alignment of conduits for the nascent polypeptide chain in the ribosome-Sec61 complex
2. Ribosomal-membrane interaction: In vitro binding of ribosomes to microsomal membranes
3. A yeast mutant defective at an early stage in import of secretory protein precursors into the endoplasmic reticulum
4. The yeast SSS1 gene is essential for secretory protein translocation and encodes a conserved protein of the endoplasmic reticulum
5. A second trimeric complex containing homologs of the sec61p complex functions in protein transport across the ER membrane of S.cerevisiae
6. A mammalian homolog of SEC61p and SECYp is associated with ribosomes and nascent polypeptides during translocation
7. Protein translocation into proteoliposomes reconstituted from purified components of the endoplasmic reticulum membrane
8. A posttargeting signal sequence recognition event in the endoplasmic reticulum membrane
9. Binding of ribosomes to the rough endoplasmic reticulum mediated by the Sec61p-complex
10. Proteins of rough microsomal membranes related to ribosome binding. I. Identification of ribophorins I and II, membrane proteins characteristic of rough microsomes
11. Posttranslational protein transport in yeast reconstituted with a purified complex of Sec proteins and Kar2p
12. Evolutionarily conserved binding of ribosomes to the translocation channel via the large ribosomal RNA
13. The binding of ribosomal subunits to endoplasmic reticulum membranes
14. Identification of aribosome receptor in the rough endoplasmic reticulum
15. The attractions of proteins for small molecules and ions
16. Identification of a membrane protein responsible for ribosome binding in rough microsomal membranes
17. Functional characterization of the 180-kD ribosome receptor in vivo