Increased progesterone secretion and 3β-hydroxysteroid dehydrogenase activity in human cumulus cells by pregnenolone is limited to the high steroidogenic active cumuli

Journal of Assisted Reproduction and Genetics

Volumn 17, Issue 8, 2000, Pages 437-444

  Bar Ami, Shalom ^a,b,c,d   Gitay Goren, Hela ^b  

^a RAMBAM MEDICAL CENTER   (Israel)

^b TECHNION ISRAEL INSTITUTE OF TECHNOLOGY   (Israel)

^c BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d Poriya Hospital   (Israel)

Author keywords

3 hydroxysteroid dehydrogenase; Cumulus cells; In vitro fertilization; Pregnenolone; Progesterone

Indexed keywords

3(OR 17)BETA HYDROXYSTEROID DEHYDROGENASE; PREGNENOLONE; PROGESTERONE;

ARTICLE; CONTROLLED STUDY; CUMULUS OOPHORUS; ENZYME ACTIVITY; FEMALE; FERTILIZATION; GRANULOSA CELL; HUMAN; HUMAN CELL; LUTEAL CELL; OOCYTE; PRIORITY JOURNAL; PROGESTERONE RELEASE; STEROIDOGENESIS;

3-HYDROXYSTEROID DEHYDROGENASES; CELL COUNT; FEMALE; FERTILIZATION IN VITRO; HUMAN; MALE; MENSTRUAL CYCLE; OOCYTES; OVARIAN FOLLICLE; PREGNENOLONE; PROGESTERONE; RADIOIMMUNOASSAY; SPERM-OVUM INTERACTIONS;

EID: 0033786920     PISSN: 10580468     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1009465218688     Document Type: Article

References (36)

1. Cell-specific expression of immunoreactive cholesterol side-chain cleavage cytochrome P-450 during follicular development in the rat ovary
2. 5-3β- and 20α-hydroxysteroid dehydrogenases and enzymes of carbohydrate oxidation during the estrous cycle
3. Periovulatory expression of cholesterol side-chain cleavage cytochrome P-450 in cumulus cells
4. Follicular steroidogenesis and its control
5. Failure of meiotic competence in human oocytes
6. Gonadotrophic control of steroidogenesis in human granulosa-lutein cells
7. Effect of cell-plating density on the steroidogenic activity of human cumulus cells
8. Altered steroidogenic pattern of human granulosa-lutein cells in relation to cumulus cell culture morphology
9. Increasing progesterone secretion in human granulosa-lutein cells induced by human follicular fluid
10. Early luteal serum progesterone concentrations are higher in pregnancy cycles
11. Use of individual human follicles to compare oocyte in vitro fertilization to granulosa cell in vitro luteinization
12. Different morphological and steroidogenic patterns in oocyte/cumulus-corona cell complexes aspirated at in vitro fertilization
13. Increasing progesterone secretion and 3β-hydroxysteroid dehydrogenase activity of human cumulus cells and granulosa-lutein cells concurrent with successful fertilization of the corresponding oocyte
14. High progesterone concentrations induce acrosome reaction with a low cytotoxic effect
15. Exocytosis in spermatozoa in response to progesterone and zona pellucida
16. Effect of steroids on oocyte maturation and atresia in mouse ovarian fragments in vitro
17. Progestins inhibit murine oocyte meiotic maturation in vitro
18. Evaluation of the trypan blue technique for determination of cell viability
19. Effect of androgen substrates on the steroidogenic pattern of cumulus cells: Correlation with cumulus culture morphology
20. In-vitro matured metaphase-I oocytes have a lower fertilization rate but similar embryo quality as mature metaphase-II oocytes after intracytoplasmic sperm injection
21. Retrieval, maturation, and fertilization of immature oocytes obtained from unstimulated patients with polycystic ovary syndrome
22. Role of antral follicle development and cumulus cells on in vitro fertilization of mouse oocytes
23. Amino acids in maturation medium and presence of cumulus cells at fertilization promote male pronuclear formation in porcine oocytes matured and penetrated in vitro
24. Developmental competence of immature pig oocytes under the influence of EGF, IGF-I, follicular fluid and gonadotropins during IVM-IVF processes
25. Modulatory actions of activin-A and follistatin on the developmental competence of in vitro-matured bovine oocytes
26. Paracrine actions of growth differentiation factor-9 in the mammalian ovary
27. Amino acid neurotransmitter receptor/chloride channels of mammalian sperm and the acrosome reaction
28. Progesterone triggers a wave of increased free calcium during the human sperm acrosome reaction
29. The effects of estrogen and progesterone on the ciliary activity in the human fallopian tubes
30. Altered steroidogenic activity of human granulosa-lutein cells at different cell densities in culture
31. Induction of maturation of cumulus-oocyte complex by gonadotropin-releasing hormone analog is associated with lower progesterone secretion
32. Expression of messenger ribonucleic acid species encoding steroidogenic enzymes in human follicles and corpora lutea throughout the menstrual cycle
33. Effects of progesterone and antiprogesterone RU486 on ovarian 3β-hydroxysteroid dehydrogenase activity during ovulation in the gonodotrophin-primed immature rat
34. Progesterone as an autocrine/paracrine regulator of human granulosa cell proliferation
35. Acute administration of a 3β-hydroxysteroid dehydrogenase inhibitor to rhesus monkeys at the midluteal phase of the menstrual cycle: Evidence for possible autocrine regulation of the primate corpus luteum by progesterone
36. Fertilization and cleavage after reinsemination of human oocytes in vitro