'Orphans' meet cholesterol

Nature Medicine

Volumn 6, Issue 10, 2000, Pages 1104-1105

  Tall, A R ^a   Costet, P ^a   Luo, Y ^a  

^a Columbia University ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ABC TRANSPORTER; BILE ACID; CHOLESTEROL; HORMONE; RETINOID;

ABSORPTION; ATHEROSCLEROSIS; BILE ACID SYNTHESIS; CHOLESTEROL BLOOD LEVEL; DISEASE ASSOCIATION; HOMEOSTASIS; HORMONE TRANSPORT; HUMAN; PRIORITY JOURNAL; RECEPTOR AFFINITY; SHORT SURVEY;

ANIMAL; ATP-BINDING CASSETTE TRANSPORTERS; CHOLESTEROL; CHOLESTEROL 7-ALPHA-HYDROXYLASE; GLYCOPROTEINS; HUMAN; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RECEPTORS, RETINOIC ACID; RECEPTORS, STEROID; TRANSCRIPTION FACTORS;

EID: 0033786843     PISSN: 10788956     EISSN: None     Source Type: Journal    
DOI: 10.1038/80433     Document Type: Short Survey

References (11)

1. Regulation of absorption and ABC1-mediated efflux of cholesterol by RXR heterodimers
2. Sensitization of diabetic and obese mice to insulin by retinoid X receptor agonists
3. Identification of a nuclear receptor for bile acids
4. Mutations in ABC1 in Tangier disease and familial high-density lipoprotein deficiency
5. Specific binding of apoA-I, enhanced cholesterol efflux and altered plasma membrane morphology in cells expressing ABC1
6. Molecular cloning of the human ATP-binding cassette transporter 1 (hABC1): Evidence for sterol-dependent regulation in macrophages
7. Sterol-dependent transactivation of the human ABC1 promoter by LXR/RXR
8. High density lipoprotein deficiency and foam cell accumulation in mice with targeted disruption of ATP-binding cassette transporter-1
9. Sterol upregulation of human CETP expression in vitro and in transgenic mice by an LXR element
10. Cholesterol and bile acid metabolism are impaired in mice lacking the nuclear oxysterol receptor LXR alpha
11. Biliary cholesterol excretion: A novel mechanism that regulates dietary cholesterol absorption