The effect of α-melanocyte stimulating hormone on colonic inflammation in the rat

Peptides

Volumn 21, Issue 8, 2000, Pages 1271-1277

  Oktar, Berna K ^a   Ercan, Feriha ^a   Yegen, Berrak Ç ^a   Alican, Inci ^a  

^a MARMARA UNIVERSITY   (Turkey)

Author keywords

Melanocyte stimulating hormone; Colitis; Neutrophils; Nitric oxide; Prostaglandins

Indexed keywords

ALPHA INTERMEDIN; ANTIINFLAMMATORY AGENT; CYCLOOXYGENASE 1 INHIBITOR; CYCLOOXYGENASE 2 INHIBITOR; MYELOPEROXIDASE; NIMESULIDE; NITRIC OXIDE; NITRIC OXIDE DONOR; NITROPRUSSIDE SODIUM; PROSTAGLANDIN; PROSTAGLANDIN SYNTHASE INHIBITOR; TRINITROBENZENESULFONIC ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; COLITIS; COLON INJURY; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVITY; FEMALE; MALE; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; RAT;

ALPHA-MSH; ANIMAL; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ANTIHYPERTENSIVE AGENTS; COLITIS; FEMALE; FREE RADICAL SCAVENGERS; INDOMETHACIN; ISOENZYMES; MALE; NITRIC OXIDE; NITRIC OXIDE DONORS; NITROPRUSSIDE; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASE; PROSTAGLANDINS; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; SULFONAMIDES; TRINITROBENZENESULFONIC ACID;

EID: 0033785735     PISSN: 01969781     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0196-9781(00)00269-2     Document Type: Article

References (31)

1. Bradley P.P., Priebat D.A., Christerser R.D., et al. Measurement of cutaneous inflammation estimation of neutrophil content with an enzyme marker . J Invest Dermatol. 78:1982;206-209.
2. Boughton-Smith N.K., Evans S.M., Hawkey C.J., et al. Nitric oxide synthase activity in ulcerative colitis and Crohn's disease. Lancet. 342:1993;338-340.
3. Boughton N.K., Evans S.M., Laszio F., et al. The induction nitric oxide synthase and intestinal vascular permeability by endotoxin in the rat. Br J Parmacol. 110:1993;1189-1195.
4. Boughton-Smith N.K., Evans S.M., Whittle B.J.R. Elevated nitric oxide synthase activity in inflamed colon from a rat model of colitis. Gut. 33:1992;S12.
5. Boughton-Smith N.K., Evans S.M., Whittle B.J.R. Characterization of nitric oxide synthase activity in the rat colonic mucosa and muscle after endotoxin and in a rat model of colitis. Agents Actions. 41:1994;223-225.
6. Cannon J.G., Tatro J.B., Reichlin S., et al. α-Melanocyte stimulating hormone inhibits immunostimulatory and inflammatory actions of interleukin 1. J Immunol. 137:1986;2232-2236.
7. Catania A., Lipton J.M. Alpha-melanocyte stimulating hormone in the modulation of host reactions. Endocr Rev. 14:1993;564-576.
8. Catania A., Rajora N., Capsoni F., et al. The neuropeptide α-MSH has specific receptors on neutrophils and reduces chemotaxis in vivo. Peptides. 17:1996;675-679.
9. Ceriani G.J., Diaz S., Murphree A., et al. The neuropeptide α-MSH inhibits experimental arthritis in rats. Neuroimmunomodulation. 1:1994;28-32.
10. Chang A.D., Ramanujam K.S., Wilson F.T. Co-expression of inducible nitric oxide synthase (iNOS), cyclo-oxygenase (COX-2) and TGF-β in rat models of colitis (abstr). Gastroenterology. 110:1996;A881.
11. Chiao H.S., Foster R., Thomas J., et al. α-Melanocyte stimulating hormone reduces endotoxin-induced liver inflammation. J Clin Invest. 97:1996;2038-2044.
12. Gue M., Bonbonne C., Fioramonti J., et al. Stress-induced enhancement of colitis in rats CRF and arginine vasopressin are not involved . Am J Physiol. 272:1987;84-91.
13. Ham E.A., Soderman D.D., Zanetti M.E., et al. Inhibition of prostaglandins of leukotriene B4 release from activated neutropihls. Proc Natl Acad Sci USA. 80:1983;4349-4353.
14. Kunkel S.L., Wiggins R.C., Chensue S.W., et al. Regulation of macrophage tumour necrosis factor production by prostaglandin E2. Biochem Biophys Res Commun. 137:1986;404-410.
15. Levine R.L., Garland D., Oliver C.N., et al. Determination of carbonyl content in oxidatively modified proteins. Methods Enzymol. 186:1990;464-478.
16. Lipton J.M., Catania A. Anti-inflammatory actions of the neuroimmunomodulator α-MSH. Immun Today. 18:1997;140-145.
17. Lipton J.M., Ceriani G., Macaluso A., et al. Antiinflammatory effects of the neuropeptide α-MSH in acute, chronic and systemic inflammation. Ann NY Acad Sci. 741:1994;137-148.
18. Lowry O.H., Rosebrough N.J., Farr A.L., et al. Protein measurement with the Folin phenol reagent. J Biol Chem. 193:1951;265-275.
19. Lundberg J.O.N., Hellstrom P.M., Lundberg J.M., et al. Greatly increased luminal nitric oxide in ulcerative colitis. Lancet. 344:1994;1673-1674.
20. Miller M.J.S., Sadowska-Krowicka A., Chontinareumol S., et al. Amelioration of chronic ileitis by nitric oxide sythase inhibition. J Pharmacol Exp Ther. 264:1993;11-16.
21. Morris G.P., Beck P.L., Herridge M.S., et al. A hapten-induced model of chronic inflammation and ulceration in the rat colon. Gastroenterology. 96:1989;795-803.
22. Mourelle M., Caellas F., Guarner F., et al. Toxic megacolon in patients with chronic ulcerative colitis may be due to induction of nitric oxide synthase. Gastroenterology. 104:1993;A749.
23. Neilly P.J.D., Gardner K.R., Kirk S.J., et al. Endotoxemia and cytokine production in experimental colitis. Br J Surg. 82:1995;1479-1482.
24. Nussler A.K., Billiar T.R. Inflammation, immunoregulation, and inducible nitric oxide synthase. J Leukoc Biol. 54:1993;171-178.
25. Rachmilewitz D., Karmeli F., Okon E., et al. Experimental colitis is ameliorated by inhibition of nitric oxide synthase activity. Gut. 36:1995;247-255.
26. Rajora N., Boccoli G., Catania A., et al. α-MSH modulated experimental inflammatory bowel disease. Peptides. 18:1997;381-385.
27. Reynolds P.D., Middleton S.J., Hunter P. High expression of iNOS in colonic mucosa in ulcerative colitis. Gut. 36:1995;A56.
28. Star R.A., Rajora N., Huang J., et al. Evidence of autocrine modulation of macrophage nitric oxide synthase by α-melanocyte stimulating hormone. Proc Natl Acad Sci USA. 92:1995;8016-8020.
29. Wallace J.L., Braquet P., Ibbotson G.C., et al. Assessment of the role of platelet activating factor in an animal model of inflammatory bowel disease. J Lipid Med. 1:1989;13-23.
30. Weidenfeld J., Crumeyrolle-Arias M., Haour F., et al. Effect of bacterial endotoxin and IL-1 on prostaglandin synthesis by the hippocampus of mouse brain role of IL-1 receptors and glucocorticoids . Neuroendocrinology. 62:1995;39-46.
31. Wilson J.F. Low permeability of the blood-brain nanomolar concentrations of immunoreactive α-melanocortin. Psychopharmacology. 96:1988;262-266.