Comparative genomic hybridization reveals recurrent enhancements on chromosome 20 and in one case combined amplification sites on 15q24q26 and 20p11p12 in glioblastomas

Cancer Genetics and Cytogenetics

Volumn 121, Issue 2, 2000, Pages 124-127

  Brunner, Christian ^a   Jung, Volker ^a   Henn, Wolfram ^a   Zang, Klaus D ^a   Urbschat, Steffi ^a,b  

^a SAARLAND UNIVERSITY   (Germany)

^b SAARLAND UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ARTICLE; ASTROCYTOMA; BRAIN TUMOR; CANCER GRADING; CANCER GROWTH; CHROMOSOME 10; CHROMOSOME 20; CHROMOSOME 20P; CHROMOSOME 7; CHROMOSOME LOSS; CLINICAL ARTICLE; COMPARATIVE GENOMIC HYBRIDIZATION; CONTROLLED STUDY; FEMALE; GENE AMPLIFICATION; GLIOBLASTOMA; HUMAN; HUMAN TISSUE; MALE; PRIORITY JOURNAL; RECURRENT CANCER; SAMPLE; TISSUE HOMOGENATE; TUMOR BIOPSY;

ADULT; AGED; AGED, 80 AND OVER; BRAIN NEOPLASMS; CHROMOSOMES, HUMAN, PAIR 15; CHROMOSOMES, HUMAN, PAIR 20; FEMALE; GENE AMPLIFICATION; GLIOBLASTOMA; HUMAN; KARYOTYPING; MALE; MIDDLE AGE; NUCLEIC ACID HYBRIDIZATION; SUPPORT, NON-U.S. GOV'T;

EID: 0033785189     PISSN: 01654608     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-4608(99)00171-5     Document Type: Article

References (7)

1. Chromosomal composition of a series of 22 human low-grade gliomas
2. Specific chromosomal abnormalities in malignant human gliomas
3. Amplification of multiple genes from chromosomal region 12q13-14 in human malignant gliomas; preliminary mapping of the amplicon shows preferential involvement of CDK4, SAS and MDM2
4. A molecular genetic model of astrocytoma histopathology
5. Increased chromosome 20 copy number detected by fluorescence in situ hybridization (FISH) in malignant melanoma
6. Molecular cytogenetic analysis of adult testicular germ cell tumours in identification of regions of consensus copy number change