Characterization of insulin and atypically processed proglucagon-derived peptides from the Surinam toad Pipa pipa (Anura:Pipidae)

Peptides

Volumn 21, Issue 9, 2000, Pages 1355-1360

  Matutte, Beverly ^a   Conlon, J Michael ^a  

^a CREIGHTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

GLP; Glucagon; Insulin; Posttranslational processing

Indexed keywords

ARGININE; ASPARAGINE; GLUCAGON; GLUCAGON LIKE PEPTIDE 1; HISTIDINE; INSULIN; LEUCINE; LYSINE; PEPTIDE; PREPROGLUCAGON; SERINE; THREONINE; TISSUE EXTRACT; TYROSINE;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; EVOLUTION; FROGS AND TOADS; MASS SPECTROMETRY; MOLECULAR SIZE; NONHUMAN; PANCREAS; PRIORITY JOURNAL; PROTEIN PROCESSING; PROTEIN PURIFICATION; PROTEIN STRUCTURE; TOAD; VERTEBRATE; XENOPUS LAEVIS;

AMINO ACID SEQUENCE; ANIMAL; EVOLUTION, MOLECULAR; GLUCAGON; INSULIN; MOLECULAR SEQUENCE DATA; PANCREAS; PEPTIDE FRAGMENTS; PIPIDAE; PROTEIN PRECURSORS; PROTEIN PROCESSING, POST-TRANSLATIONAL; SEQUENCE HOMOLOGY, AMINO ACID; SUPPORT, U.S. GOV'T, NON-P.H.S.;

ANURA; MAMMALIA; PIPA; PIPA PIPA; PIPIDAE; VERTEBRATA; XENOPUS (GENUS); XENOPUS LAEVIS;

EID: 0033783674     PISSN: 01969781     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0196-9781(00)00278-3     Document Type: Article

References (29)

1. Structure-activity studies of glucagon-like peptide-1
2. The structure 2 Zn pig insulin crystal at 1.5 A resolution
3. Isolation and structural characterization of proglucagon-derived peptides, pancreatic polypeptide and somatostatin from the urodele, Amphiuma tridactylum
4. Molecular evolution of insulin in non-mammalian vertebrates
5. Characterization of an insulin from the amphiuma (Amphibia; Urodela) with an N-terminally extended A-chain and high receptor-binding affinity
6. Primary structure of peptides derived from proglucagon isolated from the pancreas of the elasmobranch fish, Scyliorhinus canicula
7. Purification and structural characterization of insulin from a caecilian, Typhlonectes natans (Amphibia; Gymnophiona)
8. Purification and structural characterization of insulin from the lesser siren, Siren intermedia (Amphibia:Caudata)
9. Islet hormones from the African bullfrog Pyxicephalus adspersus (Anura:Ranidae); structural characterization and phylogenetic implications
10. Freeze tolerance in the wood frog Rana sylvatica is associated with unusual structural features in insulin but not in glucagon
11. Proglucagon processing in an islet cell line; effects of PC1 overexpression and PC2 depletion
12. Incomplete processing of proinsulin to insulin accompanied by elevation of Des-31,32 proinsulin intermediates in islets of mice lacking active PC2
13. Structure/activity characterization of glucagon-like peptide-1
14. The early evolution of the Amniota
15. The Xenopus proglucagon gene encodes novel GLP-1-like peptides with insulinotropic properties
16. Trout and chicken proglucagon; alternative splicing generates mRNA transcripts encoding glucagon-like peptide 2
17. The glucagon-like peptides
18. Alanine scanning mutagenesis of insulin
19. Pancreatic preproglucagon cDNA contains two glucagon-related coding sequences arranged in tandem
20. Glucagon-like peptides GLP-1 and GLP-2, predicted products of the glucagon gene, are secreted separately from pig small intestine but not pancreas
21. Structure-function analysis of a series of glucagon-like peptide-1 analogs
22. Glucagon and glucagon-like peptides in fishes
23. Isolation of peptide hormones from the pancreas of the bullfrog (Rana catesbeiana)
24. Proglucagon is processed by prohormone convertase PC2 in alpha TC1-6 cells
25. Isolation and characterization of two different insulins from an amphibian, Xenopus laevis
26. Isolation of a glucagon-containing peptide; primary structure of a possible fragment of proglucagon