메뉴 건너뛰기




Volumn 7, Issue 18, 2000, Pages 1606-1611

Multiple systemic expression of human interferon-β in mice can be achieved upon repeated administration of optimized pcTG90-lipoplex

Author keywords

Human interferon ; In vivo gene transfer; Lipoplex formulation; Repeated administration; Systemic expression

Indexed keywords

BETA INTERFERON; CATION; DNA; LIPOPLEX; LIPOSOME; LUCIFERASE; NITROGEN; PHOSPHATIDYLETHANOLAMINE; UNCLASSIFIED DRUG;

EID: 0033781138     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gt.3301289     Document Type: Article
Times cited : (21)

References (24)
  • 2
    • 0028875936 scopus 로고
    • Transfer of genes to humans: Early lessons and obstacles to success
    • (1995) Science , vol.270 , pp. 404-410
    • Crystal, R.G.1
  • 3
    • 0029147628 scopus 로고
    • Nonviral gene therapy: The promise of genes as pharmaceutical products
    • (1995) Hum Gene Ther , vol.6 , pp. 1129-1144
    • Ledley, F.D.1
  • 6
    • 0029912760 scopus 로고    scopus 로고
    • Pharmacokinetics and pharmacodynamics of recombinant human interferon-beta in healthy male volunteers
    • (1996) J Interfer Cytokine Res , vol.16 , pp. 759-764
    • Salmon, P.1
  • 11
    • 0031049765 scopus 로고    scopus 로고
    • Factors influencing the efficiency of cationic liposome-mediated intravenous gene delivery
    • (1997) Nature Biotechnol , vol.15 , pp. 167-173
    • Liu, Y.1
  • 12
    • 0002495768 scopus 로고    scopus 로고
    • Ultrastructural morphology of cationic liposome-DNA complexes for gene therapy
    • Lasic DD, Papahadjopoulos D. (eds). Medical Applications of Liposomes. Elsevier: Amsterdam
    • (1998) , pp. 395-427
    • Sternberg, B.1
  • 13
    • 0031754088 scopus 로고    scopus 로고
    • Characterization and in vivo testing of a heterogeneous cationic lipid-DNA formulation
    • (1998) Pharm Res , vol.15 , pp. 1356-1363
    • Smith, J.G.1
  • 14
    • 0032562981 scopus 로고    scopus 로고
    • Free liposomes enhance the transfection activity of DNA/lipid complexes in vivo by intravenous administration
    • (1998) Biochim Biophys Acta , vol.1372 , pp. 141-150
    • Song, Y.K.1    Liu, D.2
  • 15
    • 0032525893 scopus 로고    scopus 로고
    • Plasmid DNA encoding transforming growth factor-β1 suppresses chronic disease in a streptococcal cell wall-induced arthritis model
    • (1998) J Clin Invest , vol.101 , pp. 2615-2621
    • Song, X.-Y.1
  • 16
    • 0003378938 scopus 로고
    • Factor VIII and factor V: Biochemistry and pathophysiology
    • Albertini A, Lenfant CL, Mannucci PM, Sixma JJ (eds). Biotechnology of Plasma Proteins. Karger: Basel
    • (1991) , pp. 2155-2170
    • Vehar, G.A.1    Lawn, R.M.2    Tuddenham, E.G.D.3    Wood, W.I.4
  • 18
    • 0032892179 scopus 로고    scopus 로고
    • Systemic inhibition of tumor growth and tumor metastases by intramuscular administration of the endostatin gene
    • (1999) Nature Biotechnol , vol.17 , pp. 343-348
    • Blezinger, P.1
  • 19
    • 0033005285 scopus 로고    scopus 로고
    • Effect of immune response on gene transfer to the lung via systemic administration of cationic lipidic vectors
    • (1999) Am J Physiol , vol.276 , pp. L796-L804
    • Li, S.1
  • 20
    • 0032546804 scopus 로고    scopus 로고
    • Cationic liposomes coated with polyethylene glycol as carriers for oligonucleotides
    • (1998) J Biol Chem , vol.273 , pp. 15621-15627
    • Meyer, O.1
  • 21
    • 0033550183 scopus 로고    scopus 로고
    • Synthesis and stability of the new pentammonio lipid pcTG90, a gene transfer agent
    • (1999) Tetrahedron Lett , vol.40 , pp. 8089-8091
    • Nazih, A.1
  • 24
    • 0033040203 scopus 로고    scopus 로고
    • Effect of liposome-encapsulated clodronate pretreatment on synthetic vector-mediated gene expression in mice
    • (1999) Gene Therapy , vol.6 , pp. 448-453
    • Schughart, K.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.