Identifying the missing link between UV and p53: The role of phosphatidyl inositol kinase-related kinases

Journal of the American Academy of Dermatology

Volumn 43, Issue 4, 2000, Pages 706-707

  Nghiem, Paul ^a  

^a DANA FARBER CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; PHOSPHATIDYLINOSITOL KINASE; PROTEIN KINASE; PROTEIN P21; PROTEIN P53; RAPAMYCIN; RIBONUCLEASE;

APOPTOSIS; ATAXIA TELANGIECTASIA; B LYMPHOCYTE; CARCINOGENESIS; CELL CYCLE; DNA DAMAGE; DNA REPAIR; GENE MUTATION; HUMAN; NONHUMAN; PRIORITY JOURNAL; SCID MOUSE; SHORT SURVEY; SKIN CANCER; SQUAMOUS CELL CARCINOMA; T LYMPHOCYTE; TUMOR SUPPRESSOR GENE; ULTRAVIOLET RADIATION;

EID: 0033780844     PISSN: 01909622     EISSN: None     Source Type: Journal    
DOI: 10.1067/mjd.2000.109275     Document Type: Article

References (11)

1. Cyclin-dependent kinases are inactivated by a combination of p21 and Thr-14/Tyr-15 phosphorylation after UV-induced DNA damage
2. Involvement of the p53 tumor suppressor in repair of UV-type DNA damage
3. Sunburn and p53 in the onset of skin cancer
4. Relationship between sunlight exposure and a key genetic alteration in basal cell carcinoma
5. Basal- and squamous-cell carcinomas
6. Differential induction of transcriptionally active p53 following UV or ionizing radiation: Defects in chromosome instability syndromes?
7. DNA-dependent protein kinase is not required for the p53-dependent response to DNA damage
8. A signaling pathway to translational control
9. cDNA cloning and gene mapping of a candidate human cell cycle checkpoint protein
10. ATR disruption leads to chromosomal fragmentation and early embryonic lethality
11. Duplication of ATR inhibits MyoD, induces aneuploidy and eliminates radiation-induced G1 arrest