ICAM-1 gene is not associated with multiple sclerosis in Sardinian patients

Journal of Neurology

Volumn 247, Issue 9, 2000, Pages 677-680

  Marrosu, Maria Giovanna ^a   Schirru, Lucia ^a   Fadda, Elisabetta ^a   Mancosu, Cristina ^a   Lai, Marina ^a   Cocco, Eleonora ^a   Cucca, Francesco ^a  

^a UNIVERSITY OF CAGLIARI   (Italy)

Author keywords

Genetics; ICAM 1 gene; Multiple sclerosis

Indexed keywords

GENE PRODUCT; HLA DQ ANTIGEN; HLA DR ANTIGEN; INTERCELLULAR ADHESION MOLECULE 1;

ARTICLE; CONTROLLED STUDY; DISEASE ASSOCIATION; DNA POLYMORPHISM; EXON; FEMALE; GENE FREQUENCY; GENETIC ANALYSIS; GENETIC ASSOCIATION; HUMAN; INFLAMMATION; ITALY; MAJOR CLINICAL STUDY; MALE; MULTIPLE SCLEROSIS; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; RELAPSE; VERTICAL TRANSMISSION;

ADULT; DISEASE PROGRESSION; FEMALE; HUMAN; INTERCELLULAR ADHESION MOLECULE-1; ITALY; MALE; MICROCIRCULATION; MULTIPLE SCLEROSIS; PEDIGREE; POLYMORPHISM (GENETICS); SUPPORT, NON-U.S. GOV'T;

EID: 0033780543     PISSN: 03405354     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004150070109     Document Type: Article

References (20)

1. Reconstruction of human evolution: Bringing together genetic, archaeological, and linguistic data
2. Structure and chromosomal location of the gene for endothelial-leukocyte molecule 1
3. Alleles at four HLA class II loci determined by oligonucleotides hybridization and their associations in five ethnic groups
4. Multiple sclerosis is associated with genes within or close to the HLA-DR-DQ subregion on a normal DR15, DQ6, Dw2 haplotype
5. Multiple sclerosis in Sardinia is associated and in linkage disequilibrium with HLA-DR3 and -DR4
6. DRB1-DQA1-DQB1 loci and multiple sclerosis predisposition in the Sardinian population
7. Leukocyte-endothelial cell interactions
8. Multiple sclerosis: The increased frequency of the ICAM-1 exon 6 gene point mutation genetic type K469
9. Magnetic resonance in multiple sclerosis
10. New diagnostic criteria for multiple sclerosis: Guidelines for research protocols
11. Serial analysis of circulating adhesion molecules and TNF receptor in serum from patients with multiple sclerosis: cICAM-1 is an indicator for relapse
12. Epidemiology of multiple sclerosis in northwestern Sardinia: Further evidence for higher frequency in Sardinians compared to other Italians
13. Increased levels of circulating ICAM-1 in serum and cerebrospinal fluid of patients with active multiple sclerosis. Correlation with TNF-alpha and blood-brain barrier damage
14. Trasmission test for linkage disequilibrium: The insulin gene region and insulin-dependent diabetes mellitus (IDDM)
15. Mapping disease genes: Family-based association studies
16. The molecular basis of HLA disease association
17. In vitro intracellular adhesion molecule-1 expression on brain endothelial cells in multiple sclerosis
18. Cloning of the human gene for intercellular adhesion molecule 1 and analysis of its 5'-regulatory region
19. Polymorphisms and linkage analysis for ICAM-1 and the selectin gene cluster
20. Expression of immunologically relevant endothelial cell activation antigens on isolated central nervous microvessels from patients with multiple sclerosis