Raised levels of plasma big endothelin 1 in patients with colorectal cancer

British Journal of Surgery

Volumn 87, Issue 10, 2000, Pages 1409-1413

  Simpson, R A ^a   Dickinson, T ^a   Porter, K E ^a   London, N J M ^a   Hemingway, D M ^a  

^a LEICESTER ROYAL INFIRMARY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BIG ENDOTHELIN 1;

ADULT; AGED; ARTICLE; CANCER INVASION; CANCER STAGING; CLINICAL ARTICLE; COLORECTAL CANCER; EPITHELIUM CELL; FEMALE; HUMAN; IMMUNOHISTOCHEMISTRY; LIVER METASTASIS; MALE; PORTAL VEIN BLOOD; PRIORITY JOURNAL; PROTEIN LOCALIZATION;

ADENOCARCINOMA; ADULT; AGED; AGED, 80 AND OVER; COLORECTAL NEOPLASMS; ENDOTHELINS; FEMALE; HUMAN; LIVER NEOPLASMS; MALE; MIDDLE AGE; NEOPLASM STAGING; PROTEIN PRECURSORS; TUMOR MARKERS, BIOLOGICAL;

EID: 0033780532     PISSN: 00071323     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2168.2000.01536.x     Document Type: Article

References (20)

1. Cellular signaling by peptides of the endothelin gene family
2. Supression of liver regeneration resulting from intravenous injection of splenic glass adherent cells activated by poly I-C
3. Endothelin family in human plasma and cerebrospinal fluid
4. Endothelin in brain: Receptors, mitogenesis, and biosynthesis in glial cells
5. Endothelin stimulates c-fos and c-myc expression and proliferation of vascular smooth muscle cells
6. Endothelin stimulates phosphatidylinositol hydrolysis and DNA synthesis in brain capillary endothelial cells
7. Production of endothelin in human cancer cell lines
8. Upregulation of endothelin 1 and its precursor by IL-1beta, TNF-alpha, and TGF-beta in the PC3 human prostate cancer cell line
9. Autocrine actions of endothelin-1 as a growth factor in human ovarian carcinoma cells
10. Raised endothelin 1 levels in patients with colorectal cancer liver metastases
11. Changes in hepatic haemodynamics and hepatic perfusion index during the growth and development of hypovascular HSN sarcoma in rats
12. Metabolism of Big endothelin (1-38) and (22-38) in human circulation in relation to production of endothelin 1 (1-21)
13. Effect of endothelin-1 in man
14. Pressor effects of circulating endothelin are limited by its removal in the pulmonary circulation and by the release of prostacyclin and endothelium-derived relaxing factor
15. Perioperative plasma endothelin-1 and Big endothelin-1 concentration in elderly patients undergoing major surgical procedures
16. Patterns of recurrence following surgery alone for adenocarcinoma of the colon and rectum
17. Deranged liver blood flow patterns in the detection of liver metastases
18. A model of the hepatic perfusion index in the rat
19. Prospective assessment of the hepatic perfusion index in patients with colorectal cancer
20. Splanchnic blood flow changes in the presence of hepatic tumour: Evidence of a humoral mediator