Synthesis of tritium labeled (±)-1-[2-(triphenylmethoxy)ethyl]-3-piperidinecarboxylic acid: A possible compound to determine the efficacy of potential GABA transporter substances in vitro

Journal of Labelled Compounds and Radiopharmaceuticals

Volumn 43, Issue 11, 2000, Pages 1127-1134

  Schirrmacher, Ralf ^a   Hamkens, Wilhelm ^a   Lüddens, Hartmut ^a   Rösch, Frank ^a  

^a JOHANNES GUTENBERG UNIVERSITY   (Germany)

Author keywords

GABA transporter; Gamma amino butyric acid (GABA); GAT 3 transporter ligands; Nipecotic acid derivatives; Tritium

Indexed keywords

BUTYRIC ACID; CHELATION; LIGANDS; LITHIUM COMPOUNDS;

ACID DERIVATIVE; GAMMA AMINO BUTYRIC ACID; GAMMA AMINO BUTYRIC ACID TRANSPORTER; GAT-3 TRANSPORTER LIGAND; IN-VITRO; METHOXY; NIPECOTIC ACID; NIPECOTIC ACID DERIVATIVE; SPECIFIC ACTIVITY; TWO-STEP SYNTHESIS;

TRITIUM;

1 [2 (TRIPHENYLMETHOXY)ETHYL] 3 PIPERIDINECARBOXYLIC ACID TRITIUM H 3; 1 [2 [TRIS(4 METHOXYPHENYL)METHYL]ETHYL] 3 PIPERIDINECARBOXYLIC ACID; 4 AMINOBUTYRIC ACID; CARRIER PROTEIN; LITHIUM DERIVATIVE; NIPECOTIC ACID DERIVATIVE; RADIOLIGAND; RADIOPHARMACEUTICAL AGENT; UNCLASSIFIED DRUG;

ARTICLE; DRUG STRUCTURE; DRUG SYNTHESIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROLYSIS; ISOTOPE LABELING; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; RADIOACTIVITY; REACTION ANALYSIS; TECHNIQUE;

ILEX COOKII; TRITIUM;

EID: 0033778217     PISSN: 03624803     EISSN: None     Source Type: Journal    
DOI: 10.1002/1099-1344(20001015)43:11<1127::AID-JLCR399>3.0.CO;2-9     Document Type: Article

References (6)