Increased levels of clusterin (SGP-2) mRNA and protein accompany rat ventral prostate involution following finasteride treatment

Journal of Endocrinology

Volumn 167, Issue 2, 2000, Pages 197-204

  Astancolle, S ^a   Guidetti, G ^a   Pinna, C ^a   Corti, A ^a   Bettuzzi, S ^a  

^a UNIVERSITY OF MODENA AND REGGIO EMILIA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ANDROSTANOLONE; CLUSTERIN; FINASTERIDE; MESSENGER RNA; STEROID 5ALPHA REDUCTASE; TESTOSTERONE;

ANIMAL EXPERIMENT; ARTICLE; CELL TRANSFORMATION; CONTROLLED STUDY; EPITHELIUM CELL; GENE INDUCTION; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; NONHUMAN; ORCHIECTOMY; PRIORITY JOURNAL; PROSTATE VENTRAL LOBE; PROTEIN SYNTHESIS; RAT; SIGNAL PROCESSING;

EID: 0033778111     PISSN: 00220795     EISSN: None     Source Type: Journal    
DOI: 10.1677/joe.0.1670197     Document Type: Article

References (24)

1. Identification of genes expressed in the rat prostate that are modulated differently by castration and finasteride treatment
2. Identification of an androgen-repressed mRNA in rat ventral prostate as coding for sulphated glycoprotein 2 by cDNA cloning and sequence analysis
3. Regional and cellular distribution within the rat prostate of two mRNA species undergoing opposite regulation by androgens
4. Gene relaxation and aging: Changes in the abundance of rat ventral prostate SGP-2 (clusterin) and ornithine decarboxylase mRNAs
5. Purification and characterization of a cell-aggregating factor (clusterin), the major glycoprotein in ram rete testis fluid
6. The conversion of testosterone to 5-alpha-androstan-17-beta-ol-3-one by rat prostate in vivo and in vitro
7. Sequential androgen blockade: A biological study in the inhibition of prostatic growth
8. Human clusterin gene expression is confined to surviving cells during in vitro programmed cell death
9. Analysis of Sertoli cell-secreted proteins by two-dimensional gel electrophoresis
10. Clusterin: A role in cell survival in the face of apoptosis?
11. Clusterin biogenesis is altered during apoptosis in the regressing rat ventral prostate
12. Prostatic involution in rats induced by a novel 5 alpha-reductase inhibitor, SKandF 105657: Role for testosterone in the androgenic response
13. Prostatic ductal system in rats: Regional variation in morphological and functional activities
14. Characterization and cloning of androgen-repressed mRNAs from rat ventral prostate
15. Increased levels of clusterin mRNA in the ventral prostate of the aging rat are associated to increases in cuboidal (atrophic) cell population and not to changes in apoptotic activity
16. Differential effect of 5 alpha-reductase inhibition and castration on androgen-regulated gene expression in rat prostate
17. Evidence for atrophy and apoptosis in the ventral prostate of rats given the 5 alpha-reductase inhibitor finasteride
18. Evidence for atrophy and apoptosis in the prostates of men given finasteride
19. Clusterin: Physiologic and pathophysiologic considerations
20. Steroid 5 alpha-reductase: Two genes/two enzymes
21. TRPM-2 gene expression in normal rat ventral prostate following castration and exposure to diethylstilbestrol, flutamide, MK-906 (finasteride), and coumarin
22. Prevention of cell death induced by tumor necrosis factor alpha in LNCaP cells by overexpression of sulfated glycoprotein-2 (clusterin)
23. Effects of finasteride on the rat ventral prostate
24. Anti-androgen effects of the aromatase inhibitor, atamestane