New 1-O-Acyl α-L-rhamnopyranosides and rhamnosylated lactones from Streptomyces sp., inhibitors of 3α-hydroxysteroid-dehydrogenase (3 α-HSD)

Journal of Antibiotics

Volumn 53, Issue 9, 2000, Pages 944-953

  Hu, J F ^a   Wunderlich, D ^a   Sattler, I ^a   Hartl, A ^a   Papastavrou, I ^a   Grond, S ^a   Grabley, S ^a   Feng, X Z ^a   Thiericke, R ^a  

^a HANS KNÖLL INSTITUTE   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

1O ACYL ALPHA LEVO RHAMNOPYRANOSIDE DERIVATIVE; 2 (1 PROPEN 1 YL) 4 HYDROXYMETHYL 3 FURANYLCARBONYL ALPHA LEVO RHAMNOPYRANOSIDE; 3 (6 ALPHA RHAMNOPYRANOSYL BUT 7 ENYLIDINE) 4 HYDROXYMETHYLDIHYDROFURAN 2 ONE; 3 INDOLYLCARBONYL ALPHA LEVO RHAMNOPYRANOSIDE; 3ALPHA HYDROXYSTEROID DEHYDROGENASE; ANTIINFLAMMATORY AGENT; CARBOXYLIC ACID; ENZYME INHIBITOR; FUNGAL ENZYME; GLYCOSIDE; HYDROCORTISONE; INDOMETACIN; LACTONE DERIVATIVE; POLOXAMER; RHAMNOSE; RHAMNOSYLLACTONE A; RHAMNOSYLLACTONE B1; RHAMNOSYLLACTONE B2; RHAMNOSYLTRANSFERASE; SUGAR; TRANSFERASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG CONFORMATION; DRUG ISOLATION; DRUG SCREENING; ENZYME INHIBITION; FUNGUS CULTURE; LIVER CYTOSOL; MASS SPECTROMETRY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; RAT; STEREOCHEMISTRY; STRAIN DIFFERENCE; STREPTOMYCES; STRUCTURE ACTIVITY RELATION; ULTRAVIOLET SPECTROPHOTOMETRY;

STREPTOMYCES;

EID: 0033774640     PISSN: 00218820     EISSN: None     Source Type: Journal    
DOI: 10.7164/antibiotics.53.944     Document Type: Article

References (10)

1. The chemical screening approach
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4. Secondary metabolites by chemical screening. 39: Acyl α-L-rhamnopyranosides, a novel family of secondary metabolites from Streptomyces sp.: Isolation and biosynthesis
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10. A novel neuronal cell protecting substance, aestivophoenin C, produced by Streptomyces purpeofuscus