Red blood cell rheological alterations in hypertension induced by chronic inhibition of nitric oxide synthesis in rats

Clinical Hemorheology and Microcirculation

Volumn 22, Issue 4, 2000, Pages 267-275

  Bor Kucukatay M ^a   Yalcin O ^a   Gokalp O ^a   Kipmen Korgun, D ^a   Yesilkaya, A ^a   Baykal, A ^a   Ispir, M ^a   Senturk, U K ^a   Kaputlu, I ^a   Baskurt O K ^a,b  

^a AKDENIZ UNIVERSITY   (Turkey)

^b AKDENIZ UNIVERSITY FACULTY OF MEDICINE   (Turkey)

Author keywords

Erythrocyte aggregation; Erythrocyte deformability; Hypertension; L NAME; Nitric oxide

Indexed keywords

CALCIUM; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; NITROPRUSSIDE SODIUM;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD PRESSURE; BLOOD RHEOLOGY; CELL LEVEL; CELL TRANSPORT; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; ERYTHROCYTE AGGREGATION; ERYTHROCYTE DEFORMABILITY; HYPERTENSION; MALE; NEUROMODULATION; NEUROTRANSMISSION; NONHUMAN; RAT;

ANIMAL; CALCIUM; CYTOSOL; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; ERYTHROCYTE AGGREGATION; ERYTHROCYTE DEFORMABILITY; HEMORHEOLOGY; HYPERTENSION; LIPID PEROXIDATION; MALE; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC-OXIDE SYNTHASE; NITROPRUSSIDE; RATS; SUPPORT, NON-U.S. GOV'T; THIOBARBITURIC ACID REACTIVE SUBSTANCES;

EID: 0033774392     PISSN: 13860291     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (35)

1. R.S. Ajmani, Hypertension and hemorheology, Clin. Hemorheol. Microcirc. 17 (1997), 397-420.
2. O.K. Baskurt, Deformability of red blood cells from different species studied by resistive pulse shape analysis technique, Biorheology 33 (1996), 169-179.
3. O.K. Baskurt, Activated granulocyte induced alterations in red blood cells and protection by antioxidant enzymes, Clin. Hemorheol. 16 (1996), 49-56.
4. O.K. Baskurt and H.J. Meiselman, Activated polymorphonuclear leukocytes affect red blood cell aggregability, J. Leukoc. Biol. 63 (1998), 89-93.
5. O.K. Baskurt and H.J. Meiselman, Susceptibility of equine erythrocytes to oxidant-induced rheologic alterations, Am. J. Vet. Res. 60 (1999), 1301-1306.
6. O.K. Baskurt, H.J. Meiselman and E. Kayar, Measurement of red blood cell aggregation in a "plate-plate" shearing system by analysis of light transmission, Clin. Hemorheol. Microcirc. 19 (1998), 307-314.
7. O.K. Baskurt, A. Temiz and H.J. Meiselman, Effect of superoxide anions on red blood cell rheologic properties, Free Rad. Biol. Med. 24 (1998), 102-110.
8. G. Bianchi, P. Ferrari, D. Trizio, M. Ferrandi, L. Torielli, B.R. Barber and E. Polli, Red blood cell abnormalities and spontaneous hypertension in the rat. A genetically determined link, Hypertension 7 (1985), 319-325.
9. G. Caimi, A. Contorno, A. Serra, A. Catania, R.L. Presti, A. Sarno and G. Gerasola, Red cell metabolic parameters and rheological determinants in essential hypertension, Clin. Hemorheol. 13 (1993), 35-44.
10. 2+ content (cytosolic and total) and erythrocyte membrane fluidity in vascular atherosclerotic disease, Clin. Hemorheol. 11 (1991), 617-621.
11. T.C. Chan, D.V. Godin and M.C. Sutter, Erythrocyte membrane abnormalities in hypertension: a comparison between two animal models, Clin. Exp. Hypertens. 5 (1983), 691-719.
12. S. Chien, Red cell deformability and its relevance to blood flow, Ann. Rev. Physiol. 49 (1987), 177-192.
13. 2+ homeostasis, Biochem. Pharmacol. 55 (1998), 713-718.
14. 2+-indicator fura-2, Cell Calcium 9 (1988), 167-179.
15. E. Friederichs and H.J. Meiselman, Effects of calcium permeabilization on RBC rheologic behavior, Biorheology 31 (1994), 207-215.
16. R. Korbut and R.J. Gryglewski, Nitric oxide from polymorphonuclear leukocytes modulates red blood cell deformability in vitro, Eur. J. Pharmacol. 234 (1993), 17-22.
17. R. Korbut and R.J. Gryglewski, The effect of prostacyclin and nitric oxide on deformability of red blood cells in septic shock in rats, J. Physiol. Pharmacol 47 (1996), 591-599.
18. J.H. Laragh and B.M. Brenner, Hypertension: Pathophysiology, Diagnosis, and Management, Raven Press, New York, 1990.
19. D. Lominadze, I.G. Joshua and D.A. Schuschke, Increased erythrocyte aggregation in spontaneously hypertensive rats. Am. J. Hypertens. 11 (1998), 784-789.
20. M. London, The role of blood rheology in regulating blood pressure, Clin. Hemorheol. Microcirc. 17 (1997), 93-106.
21. G. Mchedlishvili, L. Gobejishvili and V. Beritashvili, Effect of intensified red blood cell aggregability on arterial pressure and mesenteric microcirculation, Microvasc. Res. 45 (1993), 233-242.
22. G. Mchedlishvili, B. Tsinamdzvrishvili, V. Beritashvili, L. Gobejishvili and V. Ilencko, New evidence for involvement of blood Theological disorders in rise of peripheral resistance in essential hypertension, Clin. Hemorheol. Microcirc. 17 (1997), 31-39.
23. S.N. Orlov, N.I. Pokudin and Y.V. Postnov, Calcium transport in erythrocytes of rats with spontaneous hypertension, J. Hypertens. 6 (1988), 829-837.
24. B. Sandhagen, F. Frithz, U. Waern and G. Ronquist, Increased whole blood viscosity combined with decreased erythrocyte fluidity in untreated patients with essential hypertension, J. Intern. Med. 228 (1990), 623-626.
25. G.W. Schmid-Schönbein, D. Seiffge, F.A. DeLano, K. Shen and B.W. Zweifach, Leukocyte counts and activation in spontaneously hypertensive and normotensive rats, Hypertension 17 (1991), 323-330.
26. K. Shen, F.A. DeLano, B.W. Zweifach and G.W. Schmid-Schönbein, Circulating leukocyte counts, activation, and degranulation in Dahl hypertensive rats, Circ. Res. 76 (1995), 276-283.
27. T. Shiga, N. Maeda and K. Kon, Erythrocyte rheology, Crit. Rev. Oncol. Hematol. 10 (1990), 9-48.
28. D. Starzyk, R. Korbut and R.J. Gryglewski, The role of nitric oxide in regulation of deformability of red blood cells in acute phase of endotoxaemia in rats, J. Physiol Pharmacol. 48 (1997), 731-735.
29. J. Stocks and T.L. Dormandy, The autoxidation of human red cell lipids induced by hydrogen peroxide, Br. J. Hematol. 20 (1971), 95-111.
30. H. Suzuki, A. Swei, B.W. Zweifach and G.W. Schmid-Schönbein, In vivo evidence for microvascular oxidative stress in spontaneously hypertensive rats: Hydroethidine microfluorography, Hypertension 25 (1995), 1083-1089.
31. A. Swei, F. Lacy, F.A. DeLano and G.W. Schmid-Schönbein, Oxidative stress in the Dahl hypertensive rat, Hypertension 30(1997), 1628-1633.
32. N. Uyesaka, S. Hasegawa, N. Ishioka, R. Ishioka, H. Shio and A.N. Schechter, Effect of superoxide anions on red cell deformability and membrane proteins, Biorheology 29 (1992), 217-229.
33. E. Vicaut, Microcirculation and arterial hypertension, Drugs 59 (1999), 1-10.
34. R. Walter, M. Mark, R. Gaudenz, L.G. Harris and W.H. Reinhart, Influence of nitrovasodilators and endothelin-1 on rheology of human blood in vitro, Br. J. Pharmacol. 128 (1999), 744-750.
35. R. Zatz and C. Baylis, Chronic nitric oxide inhibition model six years on, Hypertension 32 (1999), 958-964.