Imbalanced switch of the IGHG (immunoglobulin constant heavy G chain) Gm(bfn) genes in atopic childhood asthma

Allergy: European Journal of Allergy and Clinical Immunology

Volumn 55, Issue 11, 2000, Pages 1063-1068

  Oxelius, V A ^a  

^a LUND UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Childhood asthma; Genetic B cells; IGHG genes; Serum Gm allotype levels

Indexed keywords

IMMUNOGLOBULIN E; IMMUNOGLOBULIN G; IMMUNOGLOBULIN HEAVY CHAIN;

ADOLESCENT; ALLERGIC ASTHMA; ARTICLE; B LYMPHOCYTE; CHILD; CHILDHOOD DISEASE; CHROMOSOME 14Q; CLINICAL ARTICLE; CONTROLLED STUDY; GENE LOCUS; GENE REARRANGEMENT; GENE SWITCHING; HUMAN; IMMUNOGLOBULIN BLOOD LEVEL; IMMUNOGLOBULIN CONSTANT REGION; INFECTION; INHERITANCE; PRIORITY JOURNAL;

ADOLESCENT; ASTHMA; CHILD; CHROMOSOME MAPPING; GENE REARRANGEMENT; HAPLOTYPES; HUMANS; IMMUNOGLOBULIN CLASS SWITCHING; IMMUNOGLOBULIN G; IMMUNOGLOBULIN GM ALLOTYPES; IMMUNOGLOBULIN HEAVY CHAINS;

EID: 0033773325     PISSN: 01054538     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1398-9995.2000.00656.x     Document Type: Article

References (18)

1. Human immunoglobulin allotypes and mendelian polymorphism of the human immunoglobulin genes
2. Genetic B cell variation based on immunoglobulin heavy G chain (Gm) genes
3. Correlation between atopy and Gm allotypes
4. Gm allotype genes and gene dosage affecting both IgG subclass and IgE levels in atopic patients
5. Gm allotypes as indicators of nonatopic and atopic bronchial asthma
6. Development of allergy to laboratory animals is associated with particular Gm and HLA genes
7. Alternative G1m, G2m and G3m allotypes of IGHG genes correlate with atopic and nonatopic pathways of immune regulation in children with bronchial asthma
8. Different Gm allotype levels in human intravenous immunoglobulin (IVIG) preparations; survival of foreign Gm allotypes in immunodeficient patients
9. Preparation of IgG subclass allotypes from polyclonal IgG
10. Serum IgG and IgG subclass contents in different Gm phenotypes
11. Serum Gm allotype development during childhood
12. Quantitation of Gm allotypes
13. Determination of homozygosity and heterozygosity for the G2m(n) allotype by monoclonal precipitating antibody
14. Association between immunoglobulin allotypes and immune response to Haemophilus influenzae and meningococcus polysaccharides
15. Correlation between G2m(n) immunoglobulin allotype and human antibody response and susceptibility to polysaccharide encapsulated bacteria
16. Genes associated with the G2m(23) immunoglobulin allotype regulate the IgG subclass responses to Haemophilus influenzae type b polysaccharide vaccine
17. Lack of the G2m(n) allotype in IgG subclass deficiency: In IgG2 deficiency together with lack of G1m(a) and G3m(g) and in IgG3 deficiency together with lack of G1m(f) and G3m(b)
18. IgG3 deficiency: Common in obstructive lung disease