Synthesis, of (R)- and (S)-13-hydroxy-10-oxo-trans-11-octadecenoic acid and their antimutagenic activity

Biocontrol Science

Volumn 5, Issue 2, 2000, Pages 91-95

  Noguchi, M ^a   Takai, K ^a   Takei, Y ^a   Iriye, R ^a  

^a SHINSHU UNIVERSITY   (Japan)

Author keywords

Antimutagen; Antitumor; Hydroxyenone; Linoleic acid; Lipoxygenase oxidation

Indexed keywords

13 HYDROXY 10 OXO 11 OCTADECENOIC ACID; ANTINEOPLASTIC AGENT; HEPTANE; HYDROXYL GROUP; STEARIC ACID DERIVATIVE; TETRAHYDROPYRAN DERIVATIVE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BACTERIAL MUTATION; DRUG STRUCTURE; DRUG SYNTHESIS; ESCHERICHIA COLI; NONHUMAN; ULTRAVIOLET RADIATION;

EID: 0033772422     PISSN: 13424815     EISSN: None     Source Type: Journal    
DOI: 10.4265/bio.5.91     Document Type: Article

References (8)

1. Sequential enzymes of linoleic acid oxidation in corn germs: Lipoxygenase and linoleate hydroperoxide isomerase
2. Recent investigations into the lipoxygenase pathway of plants
3. A new cytotoxic compound from a water extract of corn
4. The synthesis of (R) -1- (2-oxocyclopentyliden) -2- alkanols and the (S)-forms, and their bio-antimutagenic activity against UV-induced Escherichia coli WP 2 B/r Trp
5. Antitumor activities of ketol forms of unsaturated fatty acids from a water extract of corn grain in Japanese
6. Cinnamaldehyde: Identification of an antimutagen from a crude drug, Cinnamoni cortex
7. Isolation and characterization of cytotoxic compounds from corn
8. Enantioselective synthesis of 10-oxo-11 (E)-octadecene-13-olide and related fatty acid