A turnover model of irreversible inhibition of gastric acid secretion by omeprazole in the dog

Journal of Pharmacology and Experimental Therapeutics

Volumn 295, Issue 2, 2000, Pages 662-669

  Abelo, A ^a   Eriksson, U G ^a   Karlsson, M O ^a   Larsson, H ^a   Gabrielsson, J ^a  

^a ASTRAZENECA R AND D   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

HISTAMINE; HYDROGEN POTASSIUM ADENOSINE TRIPHOSPHATASE; OMEPRAZOLE;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOG; DOSE TIME EFFECT RELATION; DRUG BLOOD LEVEL; DRUG EFFECT; DRUG MECHANISM; DRUG POTENCY; DRUG PROTEIN BINDING; ENZYME BINDING; ENZYME KINETICS; EXPERIMENTAL MODEL; HALF LIFE TIME; NONHUMAN; PRIORITY JOURNAL; STOMACH ACID SECRETION; STOMACH FISTULA;

ANIMAL; ANTI-ULCER AGENTS; BODY FLUID COMPARTMENTS; COMPARATIVE STUDY; DOGS; DRUG ADMINISTRATION SCHEDULE; GASTRIC ACID; H(+)-K(+)-EXCHANGING ATPASE; HUMAN; MODELS, BIOLOGICAL; OMEPRAZOLE; PREDICTIVE VALUE OF TESTS;

EID: 0033771722     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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