FR901469, a novel antifungal antibiotic from an unidentified fungus No.11243. I. Taxonomy, fermentation, isolation, physico-chemical properties and biological properties

Journal of Antibiotics

Volumn 53, Issue 9, 2000, Pages 912-919

  Fujie, A ^a   Iwamoto, T ^a   Muramatsu, H ^a   Okudaira, T ^a   Nitta, K ^a   Nakanishi, T ^a   Sakamoto, K ^a   Hori, Y ^a   Hino, M ^a   Hashimoto, S ^a   Okuhara, M ^a  

^a ASTELLAS PHARMA INC   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ACETIC ACID ETHYL ESTER; ACETONE; ACETONITRILE; ACULEACIN A; AGAR; AMMONIUM DERIVATIVE; ANTIBIOTIC AGENT; ANTIFUNGAL AGENT; ANTIINFECTIVE AGENT; BUTANOL; CILOFUNGIN; ECHINOCANDIN B; ECHINOCANDIN B DERIVATIVE; ENZYME INHIBITOR; FR 901469; GLUCAN SYNTHASE; GLUCOSE; HYALIN; LIPOPEPTIDE; METHANOL; MULUNDOCANDIN; NIKKOMYCIN; PAPULACANDIN B; PNEUMOCANDIN DERIVATIVE; UNCLASSIFIED DRUG; WATER; WF 11899 A;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIFUNGAL ACTIVITY; ARTICLE; CANDIDA ALBICANS; CONCENTRATION RESPONSE; CONTROLLED STUDY; CULTURE MEDIUM; DRUG ACTIVITY; DRUG CONFORMATION; DRUG DETERMINATION; DRUG ISOLATION; DRUG POTENCY; DRUG SOLUBILITY; ENZYME INHIBITION; FEMALE; FERMENTATION; FREEZE DRYING; FUNGUS; FUNGUS CULTURE; GEL CHROMATOGRAPHY; LD 50; MOUSE; NONHUMAN; POWDER; PRIORITY JOURNAL; STRUCTURE ANALYSIS; TAXONOMY; TOXICITY TESTING;

CANDIDA ALBICANS;

EID: 0033770515     PISSN: 00218820     EISSN: None     Source Type: Journal    
DOI: 10.7164/antibiotics.53.912     Document Type: Article

References (19)

1. Antibiotics that inhibit fungal cell wall development
2. Ein neuartiges polypeptide-antibiotikum aus Aspergillus nidulans var. echinudatus: Isolierung und bausteine
3. Studies on aculeacin. I. Isolation and characterization of aculeacin A
4. Pneumocandins from Zalerion arboricola. I. Discovery and isolation
5. L-671,329, A new antifungal agent. I. Fermentation and isolation
6. Pneumocandins from Zalerion arboricola, IV. Biological evaluation of natural and semisynthetic pneumocandins for activity against Pneumocystis carinii and Candida species
7. Papulacandins, a new family of antibiotics with antifungal activity. I. Fermentation, isolation, chemical and biological characterization of papulacandins A, B, C, D and E
8. WF11899A, B, and C, novel antifungal lipopeptides. I. Taxonomy, fermentation, isolation and physico-chemical properties
9. WF11899A, B, and C, novel antifungal lipopeptides. II. Biological properties
10. FR901379, A novel antifungal antibiotic
11. FK463, a novel water-soluble echinocandin lipopeptide: Synthesis and antifungal activity
12. In vitro activities of a new lipopeptide antifungal agent, FK463, against a variety of clinically important fungi
13. Efficacy of FK463, a new lipopeptide antifungal agent, in mouse models of disseminated candidiasis and aspergillosis
14. Efficacy of FK463, a new lipopeptide antifungal agent, in mouse models of pulmonary aspergillosis
15. An agar-medium for aquatic Hyphomycetes
16. Echinocandin inhibition of 1,3-β-D-glucan synthase from Candida albicans
17. Mulundocandin, an echinocandin like lipopeptide antifungal agent: Biological activities in vitro