Identification of a peptide sequence in albumin that potentiates superoxide production by microglia

Journal of Neurochemistry

Volumn 75, Issue 6, 2000, Pages 2309-2315

  Nakamura, Yoichi ^a,b   Si, Qiu Sheng ^a   Takaku, Takeshi ^a   Kataoka, Kiyoshi ^a  

^a EHIME UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b KANAZAWA UNIVERSITY   (Japan)

Author keywords

Albumin; Microglia Superoxide; Phorbol ester; Tetrapeptide

Indexed keywords

BOVINE SERUM ALBUMIN; SUPEROXIDE;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; BLOOD BRAIN BARRIER; CONTROLLED STUDY; DISULFIDE BOND; MICROGLIA; NERVE CELL LESION; NERVE DEGENERATION; NEWBORN; NONHUMAN; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; RAT;

AMINO ACID SEQUENCE; ANIMALS; BLOOD PROTEINS; CELLS, CULTURED; CHEMICAL FRACTIONATION; CHROMATOGRAPHY, GEL; DOSE-RESPONSE RELATIONSHIP, DRUG; MICROGLIA; MOLECULAR SEQUENCE DATA; PEPTIDE FRAGMENTS; RATS; SEQUENCE ANALYSIS, PROTEIN; SERUM ALBUMIN, BOVINE; SUPEROXIDES;

ANIMALIA; BOVINAE;

EID: 0033769139     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2000.0752309.x     Document Type: Article

References (17)

1. Cytotoxicity of microglia
2. Mechanisms of nitric oxide-mediated neurotoxicity in primary brain cultures
3. Atomic structure and chemistry of human serum albumin
4. Polyethylene glycol-conjugated superoxide dismutase and catalase reduce ischemic brain injury
5. Intracerebral distribution of albumin after transient cerebral ischemia: Light and electron microscopic immunocytochemical investigation
6. The inflammatory response system of brain: Implications for therapy of Alzheimer and other neurodegenerative diseases
7. Activation of microglial cells by β-amyloid protein and interferon-γ
8. The concept of microglia in relation to central nervous system disease and regeneration
9. The microglial reaction in the rat dorsal hippocampus following transient forebrain ischemia
10. Albumin stimulates uptake of calcium into subcellular stores in rat cortical astrocytes
11. Plasma albumin induces calcium waves in rat cortical astrocytes
12. Albumin enhances superoxide production in cultured microglia
13. Differential regulation of microglial activation by propentofylline via cAMP signaling
14. Reactive microgliosis
15. Amyloid beta protein primes cultured rat microglial cells for an enhanced phorbol 12-myristate 13-acetate-induced respiratory burst activity
16. Detection of free radicals during brain ischemia and reperfusion by spin trapping and microdialysis