Autoantibodies to fibrillin 1 in systemic sclerosis: Ethnic differences in antigen recognition and lack of correlation with specific clinical features or HLA alleles

Arthritis and Rheumatism

Volumn 43, Issue 11, 2000, Pages 2464-2471

  Tan, Filemon K ^a,e   Arnett, Frank C ^a   Reveille, John D ^a   Ahn, Chul ^a   Antohi, Stephan ^b   Sasaki, Takeshi ^c   Nishioka, Kioshi ^d   Bona, Constantin A ^b  

^a UNIVERSITY OF TEXAS   (United States)

^b MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^c TOHOKU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^d TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^e UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIBODY; FIBRILLIN;

AMERICAN INDIAN; ANTIBODY DETECTION; ANTIGEN RECOGNITION; ARTICLE; CAUCASIAN; CONTROLLED STUDY; DERMATOMYOSITIS; ETHNOLOGY; HUMAN; JAPAN; MAJOR CLINICAL STUDY; NEGRO; POLYMYOSITIS; PRIORITY JOURNAL; SYSTEMIC SCLEROSIS;

ALLELES; AUTOANTIBODIES; COHORT STUDIES; EPITOPES; EUROPEAN CONTINENTAL ANCESTRY GROUP; HLA ANTIGENS; HUMANS; INDIANS, NORTH AMERICAN; JAPAN; MICROFILAMENT PROTEINS; PROSPECTIVE STUDIES; SCLERODERMA, SYSTEMIC;

EID: 0033768505     PISSN: 00043591     EISSN: None     Source Type: Journal    
DOI: 10.1002/1529-0131(200011)43:11<2464::AID-ANR13>3.0.CO;2-F     Document Type: Article

References (29)

1. HLA and autoimmunity in scleroderma (systemic sclerosis)
2. Autoantibodies to the extracellular microfibrillar protein, fibrillin-1, in patients with scleroderma and other connective tissue diseases
3. Autoantibodies to the extracellular matrix microfibrillar protein, fibrillin 1, in patients with localized scleroderma
4. A tandem duplication within the fibrillin 1 gene is associated with the mouse tight skin mutation
5. Association of microsatellite markers near the fibrillin 1 gene on human chromosome 15q with scleroderma in a Native American population
6. Spontaneous occurrence of anti-fibrillin-1 autoantibodies in tight skin mice
7. Influence of ethnic background on clinical and serologic features in patients with systemic sclerosis and anti DNA topoisomerase I antibody
8. Systemic sclerosis in three U.S. ethnic groups: A comparison of clinical sociodemographic, serologic and immunogenetic determinants
9. Subcommittee for Scleroderma Criteria of the American Rheumatism Association Diagnostic and Therapeutic Criteria Committee
10. Interrelationship of major histocompatibility complex class II alleles and autoantibodies in four ethnic groups with various forms of myositis
11. Polymyositis and dermatomyositis (parts 1 and 2)
12. Association of amino acid sequences in the HLA-DQB1 first domain with the anti-topoisomerase I autoantibody response in scleroderma (progressive systemic sclerosis)
13. Structure and expression of fibrillin-2, a novel microfibrillar component preferentially located in elastic matrices
14. Primary structure and developmental expression of Fbn-1, the mouse fibrillin gene
15. Scleroderma (systemic sclerosis): Classification, subsets and pathogenesis
16. D-penicillamine therapy in progressive systemic sclerosis (scleroderma): A retrospective analysis
17. Increased prevalence of systemic sclerosis in a Native American tribe in Oklahoma: Association with an Amerindian HLA haplotype
18. The HLA-DR and DQ genes control the autoimmune response to DNA topoisomerase I in systemic sclerosis (scleroderma)
19. Purification and partial characterization of fibrillin, a cysteine-rich structural component of connective tissue microfibrils
20. Mutations on the human gene for fibrillin-1 in the Marfan syndrome and related disorders
21. Tight-skin, a new mutation of the mouse causing excessive growth of connective tissue and skeleton
22. Extracellular microfibrils are increased in localized and systemic scleroderma skin
23. Remodeling of elastic fiber components in scleroderma skin
24. Abnormalities in fibrillin-1 containing microfibrils in fibroblast cultures from systemic sclerosis (scleroderma) patients
25. B-cell deficiency does not abrogate development of cutaneous hyperplasia in mice inheriting the defective fibrillin-1 gene
26. The mouse tight skin (Tsk) phenotype is not dependent on the presence of mature T and B lymphocytes
27. An immunodominant epitope on DNA topoisomerase I is conformational in nature: Heterogeneity in its recognition by systemic sclerosis sera