Factor XIII Val34Leu and the risk of venous thromboembolism in factor V Leiden carriers

British Journal of Haematology

Volumn 111, Issue 1, 2000, Pages 118-121

  Franco, Rendrik F ^a   Middeldorp, Saskia ^a   Meinardi, Johan R ^b   Van Pampus, Elisabeth C M ^c   Reitsma, Pieter H ^a  

^a ACADEMIC MEDICAL CENTER   (Netherlands)

^b UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^c MAASTRICHT UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Factor V Leiden; Factor XIII; Mutation; Screening; Venous thromboembolism

Indexed keywords

BLOOD CLOTTING FACTOR 5; BLOOD CLOTTING FACTOR 8; LEUCINE; VALINE;

ADOLESCENT; ADULT; AGED; ARTICLE; FEMALE; GENE MUTATION; GENOTYPE; HUMAN; INCIDENCE; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RISK FACTOR; THROMBOEMBOLISM; THROMBOSIS;

ADOLESCENT; ADULT; AGE FACTORS; AGED; AGED, 80 AND OVER; CONFIDENCE INTERVALS; FACTOR V; FACTOR XIII; FEMALE; HOMOZYGOTE; HUMANS; INCIDENCE; MALE; MIDDLE AGED; MUTATION; RISK ASSESSMENT; THROMBOEMBOLISM; VENOUS THROMBOSIS;

EID: 0033768444     PISSN: 00071048     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2141.2000.02338.x     Document Type: Article

References (17)

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2. Mutation in blood coagulation factor V associated with resistance to activated protein C
3. Association of a common polymorphism in the factor XIII gene with venous thrombosis
4. Familial thrombophilia due to a previously unrecognized mechanism characterized by poor anticoagulant response to activated protein C: Prediction of a cofactor to activated protein C
5. Factor XIII Val34Leu is a genetic factor involved in the etiology of venous thrombosis
6. The Val34Leu polymorphism in the A subunit of coagulation factor XIII contributes to the large normal range in activity and demonstrates that the activation peptide plays a role in catalytic activity
7. A common coding polymorphism in the FXIII A-subunit gene (FXIIIVal34Leu) affects cross-linking activity
8. Association of a common polymorphism in the factor XIII gene with myocardial infarction
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11. Deficiency in the A-subunit of coagulation factor XIII: Two novel point mutations demonstrate different effects on transcript levels
12. A simple salting out procedure for extracting DNA from human nucleated cells
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16. Association of idiopathic venous thromboembolism with single point-mutation at Arg506 of factor V
17. On estimating the relation between blood group and disease