MR lymphography using iron oxide nanoparticles in rats: Pharmacokinetics in the lymphatic system after intravenous injection

Journal of Magnetic Resonance Imaging

Volumn 12, Issue 5, 2000, Pages 734-739

  Réty, Frédérique ^a   Clément, Olivier ^a   Siauve, Nathalie ^a   Cuénod, Charles André ^a   Carnot, Franoise ^b   Sich, Mireille ^a   Buisine, Anne ^c   Frija, Guy ^a  

^a INSERM   (France)

^b UNIVERSITÉ PARIS DESCARTES   (France)

^c Hpital Fernand Widal   (France)

Author keywords

Contrast agent; Iron; Lymph; Lymphography

Indexed keywords

CONTRAST MEDIUM; NANOPARTICLE; ULTRASMALL SUPERPARAMAGNETIC IRON OXIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CYTOLOGY; DRUG UPTAKE; FEMALE; IRON BLOOD LEVEL; LYMPH VESSEL; LYMPHATIC DRAINAGE; LYMPHATIC SYSTEM; LYMPHOGRAPHY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; RAT; THORACIC DUCT;

ANIMALS; CONTRAST MEDIA; FEMALE; INJECTIONS, INTRAVENOUS; IRON; LYMPH NODES; LYMPHOGRAPHY; MAGNETIC RESONANCE IMAGING; MODELS, ANIMAL; OXIDES; PROBABILITY; RATS; RATS, INBRED F344; SENSITIVITY AND SPECIFICITY;

EID: 0033765384     PISSN: 10531807     EISSN: None     Source Type: Journal    
DOI: 10.1002/1522-2586(200011)12:5<734::AID-JMRI10>3.0.CO;2-R     Document Type: Article

References (23)

1. Ultrasmall superparamagnetic iron oxide: Characterization of a new class of contrast agents for MR imaging
2. Interstitial MR lymphography with iron oxide particles: Results in tumor-free and VX2 tumor-bearing rabbits
3. MR lymphography using iron oxide particles. Detection of lymph node metastases in the VX2 rabbit tumor model
4. Initial clinical experience with dextran-coated superparamagnetic iron oxide for detection of lymph node metastases in patients with head and neck cancer
5. Iron oxide-enhanced MR lymphography: The evaluation of cervical lymph node metastases in head and neck cancer
6. MR imaging of pelvic lymph nodes in primary pelvic carcinoma with ultrasmall superparamagnetic iron oxide (Combidex): Preliminary observations
7. MR imaging of lymph nodes in patients with primary abdominal and pelvic malignancies using ultrasmall superparamagnetic iron oxide (Combidex)
8. Lymph node metastases: Safety and effectiveness of MR imaging with ultrasmall superparamagnetic iron oxide particles - Initial clinical experience
9. MR lymphography with superparamagnetic iron nanoparticles in rats: Pathologic basis for contrast enhancement
10. AMI-227-enhanced MR lymphography: Usefulness for differentiating reactive from tumor-bearing lymph nodes
11. Lymph nodes: Microstructural anatomy at MR imaging
12. Investigation of mechanisms influencing the accumulation of ultrasmall superparamagnetic iron oxides in lymph nodes
13. Experimental investigation of the delivery pathway of ultrasmall superparamagnetic iron oxide to lymph nodes
14. Physical and chemical properties of superparamagnetic iron oxide MR contrast agents: Ferumoxides, ferumoxtran, ferumoxsil
15. A modified Bollman's technique for canulation of the rat's thoracic duct: Lymph flow standardisation
16. The diffusion of dextrans of different molecular sizes to lymph and urine
17. Plasma, lymph and urine studies after dextran infusions
18. Mechanism of colloidal particle uptake into the lymphatic system: Basic study with percutaneous lymphography
19. Biodistribution of an ultrasmall superparamagnetic iron oxide colloid, BMS 180549, by different routes of administration
20. The effects of iron oxides on proton relaxivity
21. Transverse relaxation rate enhancement caused by magnetic particulates