Characterization of the anticonvulsant and neuroprotectant BIIR 561 CL in vitro: Effects on native and recombinant α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 362, Issue 4-5, 2000, Pages 419-426

  Weiser, T ^a   Iizuka, M ^b   Nishimura, S ^b   Akiba, I ^b   Barsoumian, E ^c   Zhou, M ^c   Steinhauser, C ^c   Brenner, M ^a   Palluk, R ^a   Wienrich, M ^a  

^a BOEHRINGER INGELHEIM PHARMA GMBH AND CO KG   (Germany)

^b Boehringer Ingelheim Co Ltd   (Japan)

^c Neurosurgery   (Germany)

Author keywords

AMPA receptor; Cortical neuron; Human glutamate receptor; Non competitive blocker; Nucleated outside out patch; Patch clamp

Indexed keywords

1 (4 AMINOPHENYL) 3,4 DIHYDRO 4 METHYL 3 METHYLCARBAMOYL 7,8 METHYLENEDIOXY 5H 2,3 BENZODIAZEPINE; 6 NITRO 7 SULFAMOYLBENZO[F]QUINOXALINE 2,3 DIONE; AMPA RECEPTOR; AMPA RECEPTOR ANTAGONIST; ANTICONVULSIVE AGENT; DIMETHYL 2 [2 (3 PHENYL 1,2,4 OXADIAZOL 5 YL)PHENOXY]ETHANAMINE; DIMETHYL[2 [2 (3 PHENYL 1,2,4 OXADIAZOL 5 YL)PHENOXY]ETHYL]AMINE; GLUTAMIC ACID; KAINIC ACID; NEUROPROTECTIVE AGENT; SODIUM; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; EMBRYO; MEMBRANE CURRENT; NERVE CELL; NERVE CELL CULTURE; NONHUMAN; NUCLEOTIDE SEQUENCE; PATCH CLAMP; RAT;

ANIMALS; ANTICONVULSANTS; BENZODIAZEPINES; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; GLUTAMIC ACID; HUMANS; HYDROGEN-ION CONCENTRATION; NEUROPROTECTIVE AGENTS; OXADIAZOLES; RATS; RECEPTORS, AMPA; RECOMBINANT PROTEINS;

EID: 0033762090     PISSN: 00281298     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002100000296     Document Type: Article

References (26)

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