ZD-0473 AstraZeneca

Current Opinion in Investigational Drugs

Volumn 1, Issue 2, 2000, Pages 263-266

  Hay, M P ^a  

^a UNIVERSITY OF AUCKLAND   (New Zealand)

Author keywords

[No Author keywords available]

Indexed keywords

AMD 494; AMD 508; AMMINEDICHLORO(2 METHYLPYRIDINE)PLATINUM; CARBOPLATIN; CISPLATIN; DRUG ANALOG; UNCLASSIFIED DRUG;

CLINICAL TRIAL; COLORECTAL CANCER; DOSE RESPONSE; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG EFFICACY; DRUG METABOLISM; DRUG SAFETY; HUMAN; LEUKOPENIA; MESOTHELIOMA; NEUTROPENIA; NONHUMAN; OVARY TUMOR; REVIEW; SOLID TUMOR; THROMBOCYTOPENIA;

ANIMALS; ANTINEOPLASTIC AGENTS; CLINICAL TRIALS; DRUGS, INVESTIGATIONAL; HUMANS; NEOPLASMS; ORGANOPLATINUM COMPOUNDS;

EID: 0033761719     PISSN: 09678298     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (22)

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2. Preclinical toxicology and pharmacokinetics of JM473 in Balb C mice
3. JM473: A novel sterically hindered platinum (II) complex showing non cross-resistance properties to cisplatin
4. Biotransformation of AMD473, a novel platinum analogue in plasma, cell culture and tissue
5. In vitro circumvention of cisplatin resistance by the novel sterically hindered platinum complex AMD473
6. Chemical, biochemical and pharmacological activity of the novel sterically hindered platinum co-ordination complex, cis[amminedichloro (2-methylpyridine)] platinum(II) (AMD473)
7. Cis-Amminedichloro(2-methylpyridine) platinum(II) (AMD473), a novel sterically hindered platinum complex: In vivo activity, toxicology, and pharmacokinetics in mice
8. Drug development pipeline: Status of JM-216 and ZD-0473
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12. Phase I and pharmacokinetic study of cis-amminedichloro (2-methylpyridine) platinum (ZD-0473), a novel sterically hindered plantinum complex, in patients with advanced solid malignancies
13. Lehman Brothers: Pharmaceuticals Europe: AstraZeneca
14. AnorMED announces first quarter results
15. AnorMED products
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17. AstraZeneca progresses key products and aims to double product portfolio value every five years
18. AstraZeneca ZD0473 platinum-based anticancer drug, licensed from AnorMED, begins phase II single agent clinical trial
19. Deutsche Bank AG - AstraZeneca - Nexium: A product or dose effect?
20. New developments and approaches in the platinum arena
21. AstraZeneca R and D pipeline: NCEs