Clinical efficacy of inhaled zanamivir for the treatment of patients with influenza B virus infection: A pooled analysis of randomised, placebo-controlled studies

Clinical Drug Investigation

Volumn 20, Issue 4, 2000, Pages 223-228

  Osterhaus, Albert D M E ^a   Hedrick, James A ^b   Henrickson, Kelly J ^c   Mäkelä, Mika J ^d   Webster, Alison ^e   Keene, Oliver N ^e  

^a ERASMUS MEDICAL CENTER   (Netherlands)

^b Kentucky Pediatric Research Institute   (United States)

^c MEDICAL COLLEGE OF WISCONSIN   (United States)

^d TURKU UNIVERSITY HOSPITAL   (Finland)

^e GLAXOSMITHKLINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

PLACEBO; SIALIDASE INHIBITOR; ZANAMIVIR;

ADULT; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; FEMALE; HUMAN; INFLUENZA; INFLUENZA VIRUS A; INFLUENZA VIRUS B; MAJOR CLINICAL STUDY; MALE; PHASE 2 CLINICAL TRIAL; PHASE 3 CLINICAL TRIAL; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RESPIRATORY TRACT DISEASE; SYMPTOMATOLOGY;

EID: 0033761421     PISSN: 11732563     EISSN: None     Source Type: Journal    
DOI: 10.2165/00044011-200020040-00003     Document Type: Article

References (5)

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2. Daly, JM, Wood, JM, Robertson JS. Cocirculation and divergence of human influenza viruses. In: Nicholson KG, Webster RG, Hay AJ, editors. Text Book of Influenza. London: Blackwell Science, 1998; 168-77
3. Drinka PJ, Gravenstein S, Krause P, et al. Outbreaks of influenza A and B in a highly immunized nursing home population. J Fam Pract 1997 Dec; 45 (6): 509-14
4. Bains WB, Luby JP, Martin SM. Severe illness with influenza B. Am J Med 1980 Feb; 68: 181-9
5. Woods JM, Bethell RC, Coates JAV, et al. 4-Guanidino-2,4-dideoxy-2,3-dehydro-N-acetylneuraminic acid is a highly effective inhibitor both of the sialidase (neuraminidase) and of growth of a wide range of influenza A and B viruses in vitro. Antimicrob Agents Chemother 1993 July; 37 (7): 1473-9