Upregulation of adhesion complex proteins and fibronectin by human keratinocytes treated with an aqueous extract from the leaves of Chromolaena odorata (Eupolin)

European Journal of Dermatology

Volumn 10, Issue 7, 2000, Pages 522-527

  Phan, T T ^a   Allen, J ^a   Hughes, M A ^a   Cherry, G ^a   Wojnarowska, F ^a  

^a OXFORD UNIVERSITY HOSPITALS NHS FOUNDATION TRUST   (United Kingdom)

Author keywords

Adhesion complex; Chromolaena odorata; Eupolin; Keratinocytes; Laminin 5; Wound healing

Indexed keywords

COLLAGEN TYPE 4; DERMATOLOGICAL AGENT; EUPOLIN; FIBRONECTIN; INTEGRIN; KALININ; LAMININ; PLANT EXTRACT; UNCLASSIFIED DRUG;

AQUEOUS SOLUTION; ARTICLE; CELL GROWTH; DRUG EFFICACY; EPITHELIUM; HERBAL MEDICINE; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; KERATINOCYTE; PLANT LEAF; PROTEIN EXPRESSION; WOUND HEALING;

CELL ADHESION; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; FIBRONECTINS; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; KERATINOCYTES; LAMININ; PLANT EXTRACTS; SENSITIVITY AND SPECIFICITY; UP-REGULATION;

EID: 0033757327     PISSN: 11671122     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (29)

1. The therapeutic effects of the extract from the leaves of Eupatorium odoratum (Eupolin) on the infection in dento-alveolitis, (summary of PhD thesis)
2. Chalcones of Eupatorium odoratum L. from Vietnam
3. An aqueous extract of the leaves of Chromolaena odorata (formerly Eupatorium odoratum) (Eupolin) inhibits hydrated collagen lattice contraction by normal human dermal fibroblasts
4. Mechanism of hemostatic activity of Eupatorium odoratum
5. Activities of Chromolaena odorata (Compositae) leaf extract against Pseudomonas aeroginosa and Streptococcus faecalis
6. Essential oil of Eupatorium odoratum
7. The use of Eupolin prepared from Eupatorium odoratum to treat soft tissue wounds
8. Pretreatment of human keratinocyte sheets with laminin 5 improves their grafting efficiency
9. Kalinin: An epithelium-specific basement membrane odhesion molecule that is a component of anchoring filaments
10. Enhanced proliferation of fibroblasts and endothelial cells treated with an extract of the leaves of Chromolaena odorata (Eupolin), A herbal remedy for treating wounds
11. Role of cadherins and integrins in regulating keratinocyte growth and differentiation
12. Different integrins mediate cell spreading, haptotaxis and lateral migration of HaCaT keratinocytes on fibronectin
13. Expression of β1, β3, β4, and β5 integrins by human epidermal keratinocytes and non-differentiating keratinocytes
14. Surface relocotion of alpha6 beta4 integrins ands assembly of hemidesmosomes in an in vitro model of wound healing
15. Beta 4 integrin is required for hemidesosome formation, cell adhesion and cell survival
16. Expression of integrins and basement membrane components by wound keratinocytes
17. Laminin 5 deposition promotes keratinocyte motility
18. Kalinin is more efficient than laminin in promoting adhesion of primary keratinocytes and some other epithelial cells and has different requirements for integrin receptors
19. Laminin-5 inhibits keratinocyte migration
20. Epiligrin, o new cell adhesion ligand for integrin α3β1 in epithelial basement membranes
21. Differential expression of laminin isoforms and β4 integrin epitopes in the basement membrane zone of normal human skin and basal cell carcinomas
22. Secretion of type IV collagen by keratinocytes of human adult
23. The effect of exogenous fibronectin on wound breaking strength
24. Fibronectin and fibrin provide a provisional matrix for epidermal cell migration during wound re-epithelialisation
25. Humon keratinocytes synthesize, secrete and deposit fibronectin in the pericellular matrix
26. Fibronectin enhances healing of excised wounds in rats
27. Degradation of fibronectin and vitronectin in chronic wound fluid: Analysis by cell clotting, immunoblotting, and cell adhesion assays