Thyroglobulin repression of thyroid transcription factor 1 (TTF-1) gene expression is mediated by decreased DNA binding of nuclear factor I proteins which control constitutive TTF-1 expression

Molecular and Cellular Biology

Volumn 20, Issue 22, 2000, Pages 8499-8512

  Nakazato, M ^a   Chung, H K ^a   Ulianich, L ^a   Grassadonia, A ^a   Suzuki, K ^a   Kohn, L D ^a  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

NUCLEAR FACTOR I; THYROGLOBULIN; THYROID TRANSCRIPTION FACTOR 1;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENE REPRESSION; HORMONAL REGULATION; HORMONE ACTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DNA BINDING; RAT; THYROID CELL;

AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; CATTLE; CCAAT-ENHANCER-BINDING PROTEINS; CELLS, CULTURED; DIAMIDE; DNA; DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION; MOLECULAR SEQUENCE DATA; NFI TRANSCRIPTION FACTORS; NUCLEAR PROTEINS; OLIGONUCLEOTIDES; PROMOTER REGIONS (GENETICS); PROTEIN ISOFORMS; RATS; REGULATORY SEQUENCES, NUCLEIC ACID; THYROGLOBULIN; THYROID GLAND; TRANSCRIPTION FACTORS; Y-BOX-BINDING PROTEIN 1;

EID: 0033756193     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.20.22.8499-8512.2000     Document Type: Article

References (58)

1. Thyroid cells in culture
2. The DNA binding activity and the dimerization ability of the thyroid transcription factor I are redox regulated
3. Identification of a conserved oxidation-sensitive cysteine residue in the NFI family of DNA-binding proteins
4. Thioltransferase (glutaredoxin) reactivates the DNA-binding activity of oxidation-inactivated nuclear factor I
5. A CCAAT box confers cell-type-specific regulation on the Xenopus hsp70 gene in oocytes
6. Expression patterns of the four nuclear factor I genes during mouse embryogenesis indicate a potential role in development
7. Thyroid transcription factor 1 activates the promoter of the thyrotropin receptor gene
8. A thyroid-specific nuclear protein essential for tissue-specific expression of the thyroglobulin promoter
9. Thyroglobulin interactions with thyroid plasma membranes. The existence of specific receptors and their potential role
10. Thyroglobulin interactions with thyroid membranes. Relationship between receptor recognition of N-acetylglucosamine residues and the iodine content of thyroglobulin preparations
11. The transcription factor nuclear factor I mediates repression of the GLUT4 promoter by insulin
12. 2+ and iodide efflux induced by thyrotropin and by the stimulation of alpha 1-adrenergic receptors in cultured rat thyroid cells
13. 'Touchdown' PCR to circumvent spurious priming during gene amplification
14. Isolation and characterization of the canine thyroglobulin gene promoter region
15. - symporter gene
16. Cell-type-specific expression of the rat thyroperoxidase promoter indicates common mechanisms for thyroid-specific gene expression
17. Multiple genes encode nuclear factor 1-like proteins that bind to the promoter for 3-hydroxy-3-methylglutaryl-coenzyme A reductase
18. Amino-terminal domain of NFI binds to DNA as a dimer and activates adenovirus DNA replication
19. Analysis of nuclear factor I binding to DNA using degenerate oligonucleotides
20. Isolation of human DNA sequences that bind to nuclear factor I, a host protein involved in adenovirus DNA replication
21. Origin of adenovirus DNA replication. Role of the nuclear factor I binding site in vivo
22. Nuclear factor 1 interacts with five DNA elements in the promoter region of the human cytomegalovirus major immediate early gene
23. Gene structure and expression of human thyroid transcription factor-1 in respiratory epithelial cells
24. Role of the cyclic adenosine 3',5'-monophosphate response element in efficient expression of the rat thyrotropin receptor promoter
25. Redox regulation of thyroid-transcription factors. Pax-8 and TTF-1, is involved in their increased DNA-binding activities by thyrotropin in rat thyroid FRTL-5 cells
26. CTD-like sequences are important for transcriptional activation by the proline-rich activation domain of CTF1
27. Proline-rich activator CTF1 targets the TFIIB assembly step during transcriptional activation
28. The T/ebp null mouse: Thyroid-specific enhancer-binding protein is essential for the organogenesis of the thyroid, lung, ventral forebrain, and pituitary
29. Thyroglobulin interactions with thyroid membranes: Implications for regulation of thyroid hormone formation in thyroglobulin
30. The thyrotropin receptor
31. Formation of disulfides with diamide
32. Glial fibrillary acidic protein transcription responses to transforming growth factor-beta1 and interleukin-1 beta are mediated by a nuclear factor-1-like site in the near-upstream promoter
33. Transcription factor nuclear factor I proteins form stable homo- and heterodimers
34. Transcription of the rat p53 gene is mediated by factor binding to two recognition motifs of NFI-like protein
35. Recognition site of nuclear factor I, a sequence-specific DNA-binding protein from HeLa cells that stimulates adenovirus DNA replication
36. Expression of thyroid transcription factor 1 gene can be regulated at the transcriptional and posttranscriptional levels
37. The N-acetylglucosamine-specific receptor of the thyroid. Binding characteristics, partial characterization, and potential role
38. Thyroid-specific enhancer-binding protein (T/EBP): cDNA cloning, functional characterization, and structural identity with thyroid transcription factor TTF-1
39. Transcription of the thyroid transcription factor-1 (TTF-1) gene from a newly defined start site: Positive regulation by TTF-1 in the thyroid
40. Four conserved cysteine residues are required for the DNA binding activity of nuclear factor I
41. The TGGCA protein binds to the MMTV-LTR, the adenovirus origin of replication, and the BK virus enhancer
42. Multiple transcripts encoded by the thyroid-specific enhancer-binding protein (T/EBP)/thyroid-specific transcription factor-1 (TTF-1) gene: Evidence of autoregulation
43. A novel thyroid transcription factor is essential for thyrotropin-induced up-regulation of Na+/I- symporter gene expression
44. Purification of a NFI-like DNA-binding protein from rat liver and cloning of the corresponding cDNA
45. Tyrosine phosphorylation regulates the DNA binding activity of a nuclear factor 1-like repressor protein
46. A family of human CCAAT-box-binding proteins active in transcription and DNA replication: Cloning and expression of multiple cDNAs
47. High affinity binding site for nuclear factor I next to the hepatitis B virus S gene promoter
48. Binding of thyroglobulin to bovine thyroid membranes. Role of specific amino acids in receptor recognition
49. Thyroid-specific expression and cyclic adenosine 3',5'-monophosphate autoregulation of the thyrotropin receptor gene involves thyroid transcription factor-1
50. The tissue-specific expression of the thyroglobulin gene requires interaction between thyroid-specific and ubiquitous factors
51. Follicular thyroglobulin suppresses iodide uptake by suppressing expression of the sodium/iodide symporter gene
52. Autoregulation of thyroid-specific gene transcription by thyroglobulin
53. Thyroglobulin: A master regulator of follicular function via transcriptional suppression of thyroid specific genes
54. In vivo expression of thyroid transcription factor-1 RNA and its relation to thyroid function and follicular heterogeneity: Identification of follicular thyroglobulin as a feedback suppressor of thyroid transcription factor-1 RNA levels and thyroglobulin synthesis
55. Thyroglobulin regulates follicular function and heterogeneity by suppressing thyroid-specific gene expression
56. Follicular thyroglobulin (TG) suppression of thyroid-restricted genes involves the apical membrane asialoglycoprotein receptor and TG phosphorylation
57. Transcriptional activation of NFI/CTF1 depends on a sequence motif strongly related to the carboxyterminal domain of RNA polymerase II
58. Megalin (gp330): A putative endocytic receptor for thyroglobulin (Tg)