Inflammatory activity as an indicator of water quality: The use of human whole blood cultures

Journal of Immunoassay

Volumn 21, Issue 4, 2000, Pages 387-399

  Pool, Edmund J ^a   Van Wyk, Johannes H ^a   Leslie, Alison ^a  

^a STELLENBOSCH UNIVERSITY   (South Africa)

Author keywords

IL 6; Inflammatory activity; Water quality; Whole blood culture

Indexed keywords

DRINKING WATER; INTERLEUKIN 6; RIVER WATER;

ARTICLE; BLOOD CULTURE; CYTOKINE RELEASE; HEALTH HAZARD; HUMAN; IMMUNOASSAY; INFLAMMATION; SOUTH AFRICA; WATER CONTAMINATION; WATER QUALITY;

EID: 0033752728     PISSN: 01971522     EISSN: None     Source Type: Journal    
DOI: 10.1080/01971520009349544     Document Type: Article

References (18)

1. Baumann, H.; Gauldie, J. The acute phase response. Immunol. Today 1994; 15: 74-80.
2. Mimms, C.A. The pathogenesis of Infectious Disease. London: Academic Press; San Diego. 1990,
3. Gauldie, J., Richards, C., Harnish, D., Lansdorp, P., Baumann, H. Interferon beta2/ B-cell stimulatory factor type 2 shares identity with monocyte-derived hepatocyte-stimulating factor and regulates the major acute phase protein response in liver cells. Proc. Natl. Acad. Sei. U.S.A. 1987; 84(20): 7251-5.
4. Department of Constitutional Development RSA. Municipal Infrastructure framework. 1997a.
5. Couper, I., Walker, A.R. Cent. Causes of death in a rural hospital in South Africa. Afr. J. Med. 1997; 43(8): 219-22.
6. Van Schirning, Y.E., Kfur, R., Cabelli, V., Franklin, L., Joubert, G. Morbidity among bathers exposed to polluted seawater. A prospective study. S. Afr. Med. J. 1972; 81(11): 543-6.
7. rd edition). The Benjamin/Cummings Publishing Company, Inc. 1993. Chapter 7.
8. Pool, E.J., Bouic, P.J. The detection of pyrogens in sera from patients with symptoms of sepsis using an ex vivo whole blood culture assay. J. Immunoassay 1999; 20(1&2): 1-11.
9. Pool, E.J., Johaar, G., James, S., Petersen, I., Bouic, P. J. The detection of pyrogens in blood products using an ex vivo whole blood culture assay. Immunoassay 1998, 19(2&3): 95-111.
10. Rafferty, B., Mower, J.A., Tantak, Y.S., Poole, S. Measurement of cytokine production by the monocytic cell line Mono Mac 6 using novel immunoradiometric assays for IL-1β and IL-6. J. Immunol. Methods 1991;144: 69-76.
11. Duff, G.W. and Atkins, E. The detection of endotoxins by in vitro production of endogenous pyrogen: comparison with Limulus Amoebocyte Lysate gelation. J. Immunol. Methods 1982;52: 323-31.
12. Poole, S., Thorpe, R., Meager, A., Hubbard, A. and Gearing A.J.H. Detection of pyrogens by cytokine release. Lancet 1988;January 16: 130.
13. Poole, S., Thorpe, R., Meager, A. and Gearing, A.J.H. Assay of pyrogenic contamination in pharmaceuticals by cytokine release from monocytes. Dev. Biol. Stan. 1988;69: 121-23.
14. Finch-Arietta, M.B. and Cochran, F.R. Cytokine production in whole blood er vivo. Agents Actions 1991 ;34: 49-52.
15. Meyer, O. Superantigens and their implication in autoimmune diseases. Presse. Med. 1995;24(25): 1171-7.
16. Hu, W.J., Zhang, G.S., Chu, F.S., Meng, H.D. and Meng, Z.H. Purification and partial characterization of Flavotoxin A. Appl. Environ. Microbiol. 1984;48(4): 690-3.
17. Fennrich, S., Fisher, M., Hartung, T., Lexa, P., Montag-Lessing, T., Sonntag, H.G., Weigandt, M. and Wendel, A. Detection of endotoxins and other pyrogens using human whole blood. Dev. Biol. Stand. 1999;101: 131-9.
18. Pool, E.J. and Bouic, P.J. Differentiation between endotoxin and nonendotoxin pyrogens in human albumin solutions using an ex vivo whole blood culture assay. J. Immunoassay 1999, 20(1&2): 79-89.