Reevaluating cancer risk estimates for short-term exposure scenarios

Toxicological Sciences

Volumn 58, Issue 1, 2000, Pages 32-42

  Halmes, N Christine ^a   Roberts, Stephen M ^b,c   Tolson, J Keith ^b,c   Portier, Christopher J ^b,c  

^a TERRA Inc   (United States)

^b UNIVERSITY OF FLORIDA   (United States)

^c NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

Cancer bioassays; Carcinogenicity; Estimating cancer risks; Risk assessment; Stop exposure studies

Indexed keywords

1,3 BUTADIENE; ANISOLE DERIVATIVE; CARCINOGEN; COUMARIN; COUMARIN DERIVATIVE; EUGENOL; FURAN DERIVATIVE; HEXACHLOROCYCLOPENTADIENE; OXAZEPAM; PENTACHLOROPHENOL; SALAZOSULFAPYRIDINE;

ARTICLE; BIOASSAY; CANCER RISK; CHEMICAL CARCINOGENESIS; ENVIRONMENTAL EXPOSURE; HUMAN; MAXIMUM LIKELIHOOD METHOD; RISK ASSESSMENT;

EID: 0033752638     PISSN: 10966080     EISSN: None     Source Type: Journal    
DOI: 10.1093/toxsci/58.1.32     Document Type: Article

References (34)

1. Relative susceptibility of animals and humans to the cancer hazard posed by 2,3,7,8-tetrachlorodibenzo-p-dioxin using internal measures of dose
2. Some biological aspects of skin carcinogenesis
3. Using the biological two-stage model to assess risk from short-term exposures
4. The multistage model with a time-dependent dose pattern: Applications to carcinogenic risk assessment
5. Comment on 'Relative susceptibility of animals and humans to the cancer hazard posed by 2,3,7,8-tetrachlorodibenzo-p-dioxin using internal measures of dose'
6. Carcinogenic potency of alkylating agents in rodents and humans
7. Cancer mortality among workers at a butadiene production facility
8. The effect of age and exposure duration on cancer induction by a known carcinogen in rats, mice, and hamsters
9. Zur Geschichte des Gaskrieges
10. Quantifying the carcinogenicity of antineoplastic drugs
11. Using average lifetime dose rate for intermittent exposures to carcinogens
12. Critical assessment of epidemiologic studies on the human carcinogenicity of 1,3-butadiene and styrene
13. Mortality of a cohort of workers ill the styrene-butadiene polymer manufacturing industry
14. Comparative response in carcinogenesis bioassay as a function of age at first exposure
15. Carcinogenicity of 1,3-butadiene in C57BL/6 x C3H F1 mice at low exposure concentrations
16. Cancer risk assessment with intermittent exposure
17. Statistical properties of a two-stage model of carcinogenesis
18. Testing for increased carcinogenicity using a survival-adjusted quantal response test