Amino acid supplementation improves cell-specific functions of the rat hepatocytes exposed to human plasma

Tissue Engineering

Volumn 6, Issue 5, 2000, Pages 497-504

  Washizu, Junji ^a   Chan, Christina ^a   Berthiaume, Françyois ^a   Tompkins, Ronald G ^a   Toner, Mehmet ^a   Yarmush, Martin L ^a  

^a SHRINERS HOSPITALS FOR CHILDREN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALBUMIN; COLLAGEN GEL; HYDROCORTISONE; INSULIN; UREA;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL CULTURE; CELL FUNCTION; CELL STRUCTURE; CONTROLLED STUDY; FEMALE; INTRAHEPATIC BILE DUCT; LIVER FAILURE; LIVER FUNCTION; NONHUMAN; PLASMA; PRIORITY JOURNAL; PROTEIN SYNTHESIS; RAT; SUPPLEMENTATION;

ALBUMINS; AMINO ACIDS; ANIMALS; CELLS, CULTURED; CULTURE MEDIA; FEMALE; GLUCAGON; HEPATOCYTES; HUMANS; HYDROCORTISONE; INSULIN; LIVER; RATS; RATS, INBRED LEW; UREA;

EID: 0033752395     PISSN: 10763279     EISSN: None     Source Type: Journal    
DOI: 10.1089/107632700750022143     Document Type: Article

References (24)

1. Fulminant hepatic failure: Summary of a workshop
2. Clinical experience with a bioartificial liver in the treatment of severe liver failure. A phase I clinical trial
3. Assessment of artificial liver support technology
4. Hepatocyte liver-assist systems-a clinical update
5. Performance of plasma-perfused, microencapsulated hepatocytes: Prospects for extracorporeal liver support
6. Extracorporeal application of a gel-entrapment, bioartificial liver: Demonstration of drug metabolism and other biochemical functions
7. Microcarrier culture of hepatocytes in whole plasma for use in liver support bioreactors
8. Culture of a differentiated liver cell line, Hep G2, in serum with application to a bioartificial liver: Effect of supplementation of serum with amino acids
9. In vitro function of porcine hepatocyte spheroids in 100% human plasma
10. A hybrid artificial liver system. Function of cultured monolayer pig hepatocytes in plasma from hepatic failure patients
11. Effects of plasma exposure on cultured hepatocytes: Implications for bioartificial liver support
12. Extracorporeal plasma perfusion of cultured hepatocytes: Effect of intermittent perfusion on hepatocyte function and morphology
13. Effect of extracellular matrix topology on cell structure, function, and physiological responsiveness: Hepatocytes cultured in a sandwich configuration
14. Hepatocyte function and extracellular matrix geometry: Long-term culture in a sandwich configuration
15. Long-term in vitro function of adult hepatocytes in a collagen sandwich configuration
16. Effect of collagen gel configuration on the cytoskeleton in cultured rat hepatocytes
17. Preparation of isolated rat liver cells
18. Rapid determination of urea nitrogen in serum or plasma without deproteinization
19. Glycine cytoprotection during lethal hepatocellular injury from adenosine triphosphate depletion
20. Inhibition of nonlysosomal calcium-dependent proteolysis by glycine during anoxic injury of rat hepatocytes
21. 4
22. Plasma membrane and mitochondrial transport of hepatic reduced glutathione
23. Translational and pretranslational regulation of protein synthesis by amino acid availability in primary cultures of rat hepatocytes
24. Effect of amino acid limitation on the expression of 19 genes in rat hepatoma cells