Acidic fibroblast growth factor inhibits junctional communication of Schwann cells in culture

Neurological Research

Volumn 22, Issue 7, 2000, Pages 685-691

  Reimers, D ^a   Prieto, R ^a   Gimenez Gallego, G ^a   Cuevas, P ^a   Barrio, L C ^a  

^a HOSPITAL RAMÓN Y CAJAL   (Spain)

Author keywords

Connexin 32; Dye coupling; Fibroblast growth factor; Peripheral neuropathy; Schwann cell

Indexed keywords

ACIDIC FIBROBLAST GROWTH FACTOR; CARBOXYFLUORESCEIN; CONNEXIN 32; HEPARIN; PROTEIN TYROSINE KINASE; PROTEIN TYROSINE KINASE INHIBITOR;

ANIMAL CELL; ARTICLE; CELL COMMUNICATION; CELL PROLIFERATION; ENZYME INHIBITION; GAP JUNCTION; MYELINATION; NERVE CELL CULTURE; NONHUMAN; RAT; SCHWANN CELL;

EID: 0033748342     PISSN: 01616412     EISSN: None     Source Type: Journal    
DOI: 10.1080/01616412.2000.11740740     Document Type: Article

References (51)

1. Gap junctions: New tools, new answers, new questions
2. Connections with connexins: The molecular basis of direct intercellular signaling
3. Genetic diseases and gene knockouts reveal diverse connexin functions
4. Connexin mutations in X-linked Charcot-Marie-Tooth disease
5. Functional gap junctions in the Schwann cell myelin sheath
6. Connexin 32 is a myelin-related protein in the PNS and CNS
7. Connexin-32 gene expression in rat sciatic nerves and cultured Schwann cells
8. Schwann cell function depends upon axonal signals and basal lamina components
9. Schwann cell precursors and their development
10. Schwann cell early lineage, regulation of proliferation and control of myelin formation
11. Platelet-derived growth factors and fibroblast growth factors are mitogens for rat Schwann cells
12. Mitogenic response of rat Schwann cells to fibroblast growth factor is potentiated by increased intracellular cyclic AMP levels
13. Schwann cell properties: 3. C-fos expression, bFGF production, phagocytosis and proliferation during Wallerian degeneration
14. Distribution of fibroblast growth factor in cultured dorsal root ganglion neurons and Schwann cells. I. Localization during maturation in vitro
15. Studies on cultured rat Schwann cells. I. Establishment of purified populations from cultures of peripheral nerve
16. High-level synthesis in Escherichia coli of shortened and full-length human acidic fibroblast growth factor and purification in a form stable in aqueous solutions
17. Nerve growth factor receptors on cultured Schwann cells
18. Axons regulate Schwann cell expression of the major myelin and NGF receptor genes
19. Growth factor signaling by receptor tyrosine kinases
20. Protein kinases and phosphatases
21. Growth factors modulate junctional cell-to-cell communication
22. Altered regulation of intercellular communication by epidermal growth factor, transforming growth factor-β and peptide hormones in normal human keratinocytes
23. Dissociation of PDGF receptor tyrosine kinase activity from PDGF-mediated inhibition of gap junctional communication
24. Fibroblast growth factor-2 decreases metabolic coupling and stimulates phosphorylation as well as masking of connexin-43 epitopes in cardiac myocytes
25. Basic fibroblast growth factor increases junctional communication and connexin 43 expression in microvascular endothelial cells
26. Transforming growth factor β1 and forskolin modulate gap junctional communication and cellular phenotype of cultured Schwann cells
27. Fibroblast growth factors
28. Fibroblast growth factors: Activities and significance of non-neurotrophin growth factors
29. Fibroblast growth factors, proteins with a broad spectrum of biological activities
30. Establishment of adult rat Schwann cell cultures: Effect of bFGF, α-MSH, NGF, PDGF and TGF-β on cell cycle
31. Structural abnormalities and deficient maintenance of the peripheral nerve myelin in mice lacking the gap junction protein connexin32
32. Negative regulation of the Po gene in Schwann cells: Suppression of Po mRNA and protein induction in cultured Schwann cells by FGF2 and TGFβ1, TGFβ2 and TGFβ3
33. Acidic fibroblast growth factor enhances peripheral nerve regeneration in vivo
34. Acidic and basic fibroblast growth factors in the nervous system: Distribution and differential alteration of levels after injury of central versus peripheral nerve
35. Acidic fibroblast growth factor prevents post-axotomy neuronal death of the newborn rat facial nerve
36. Response of Schwann cells to mitogens in vitro is determined by pre-exposure to serum, time in vitro and developmental age
37. Pure brain-derived acidic fibroblast growth factor is a potent angiogenic vascular endothelial cell mitogen with sequence homology to interleukin I
38. The ins and outs of fibroblast growth factors
39. Heparin-induced oligomerization of FGF molecules is responsable for FGF receptor dimerization, activation and cell proliferation
40. Structural basis for FGF receptor dimerization and activation
41. Molecular cloning and characterization of N-syndecan, a novel transmembrane heparan proteoglycan
42. Processing and subcellular distribution of the Schwann cell lipid-anchored heparan sulfate proteoglycan and identification as glypican
43. A dual receptor system is required for basic fibroblast growth factor activity
44. Basic fibroblast growth factor supports the survival of cerebral cortical neurons in primary culture
45. HSF/SF inhibits junctional communication
46. Biochemical analysis of connexin43 intracellular transport, phosphorylation, and assembly into gap junction plaques
47. Tyrosine phosphorylation of gap junction protein connexin43 is required for pp60(V-src)-induced inhibition communication
48. Epidermal growth factor disrupts junctional communication and induces phosphorylation of connexin43 on serine
49. Phosphorylation shifts unitary conductance and modifies voltage dependent kinetics of human connexin43 gap junction channels
50. Characterization of mitogen-activated protein kinase phosphorylation sites on the connexin-43 gap junction protein
51. Phosphorylation of connexin-32 by epidermal growth factor receptor tyrosine kinase