Contribution of upregulated airway endothelin-1 expression to airway smooth muscle and epithelial cell DNA synthesis after repeated allergen exposure of sensitized Brown-Norway rats

American Journal of Respiratory Cell and Molecular Biology

Volumn 23, Issue 5, 2000, Pages 618-625

  Salmon, M ^a   Liu, Y C ^a   Mak, J C W ^a   Rousell, J ^a   Huang, T J ^a   Hisada, T ^a   Nicklin, P L ^a   Fan Chung, K ^a  

^a NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALIA; RATTUS NORVEGICUS;

EID: 0033746875     PISSN: 10441549     EISSN: None     Source Type: Journal    
DOI: 10.1165/ajrcmb.23.5.3909     Document Type: Article

References (53)

1. A comparison of the quantitative anatomy of the bronchi in normal subjects, in status asthmaticus, in chronic bronchitis, and in emphysema
2. Cellular hypertrophy and hyperplasia of airway smooth muscles underlying bronchial asthma: A 3-D morphometric study
3. Relationship between airway wall thickness and airway hyperresponsiveness
4. Damage of the airway epithelium and bronchial reactivity in patients with asthma
5. Subepithelial fibrosis in the bronchi of asthmatics
6. Muscle and mucus gland size in the major bronchi of patients with chronic bronchitis, asthma and asthmatic bronchitis
7. Marked goblet cell hyperplasia with mucus accumulation in the airways of patients who died of severe acute asthma attack
8. Endothelin: A novel vasoconstrictor peptide as potent bronchoconstrictor
9. Role of endothelin-1 in regulating proliferation of cultured rabbit airway smooth muscle cells
10. Endothelin-1 promotes mitogenesis in airway smooth muscle cells
11. Endothelin-1-induced potentiation of human airway smooth muscle proliferation: An ET(A) receptor-mediated phenomenon
12. ET-1 cooperates with EGF to induce mitogenesis via a PTX-sensitive pathway in airway smooth muscle
13. Endothelin-1 stimulates proliferation of normal airway epithelial cells
14. Stimulation of the hydrolysis of phosphatidylinosotol 4,5-biphosphate and phosphatidylcholine by endothelin, a complete mitogen for Rat-1 fibroblasts
15. Effects of endothelins on collagen turnover in cardiac fibroblasts
16. Endothelin regulation of mucus glycoprotein secretion from feline tracheal submucosal glands
17. Endothelin-1 stimulates human monocytes in vitro to release TNF-α, IL-1β and IL-6
18. ET-1 released histamine from guinea pig pulmonary but not peritoneal mast cells
19. Endothelin receptor antagonists inhibit antigen-induced lung inflammation in micc
20. Levels of endothelin in the broncheoalveolar lavage fluid of patients with symptomatic asthma and reversible airflow obstruction
21. Endothelin immunoreactivity of airway epithelium in asthmatic patients
22. Repeated allergen exposure induces airway smooth muscle and epithelial cell DNA synthesis and airway remodelling in sensitised Brown-Norway rats
23. Involvement of cysteinyl leukotrienes in airway smooth muscle cell DNA synthesis after repeated allergen exposure in sensitized Brown-Norway rats
24. In vitro characterization of Ro-46-2005, a novel synthetic non-peptide endothelin antagonist of ETA and ETB receptors
25. Pharmacological characterization of bosentan, a new potent active nonpeptide endothelin receptor antagonist
26. Characterization of allergen-induced bronchial hyperresponsiveness and airway inflammation in actively sensitized Brown-Norway rats
27. cDNA cloning, sequence analysis and tissue distribution of rat preproendothelin-1 mRNA
28. Single-step method of RNA isolation by guanidium thiocyanate-chloroform extraction
29. Localization of endothelin-like immunoreactivity in airway epithelium of rats and mice
30. Increased expression of endothelin in bronchial epithelial cells of asthmatic patients and effect of corticosteroids
31. Acute pulmonary alveolar hypoxia increases lung and plasma endothelin-1 levels in conscious rats
32. Normobaric hypoxia stimulates endothelin-1 gene expression in the rat
33. Increased synthesis and release of endothelin-1 during the initial phase of airway inflammation
34. Contractile activity of three endothelins (ET-1, ET-2, ET-3) on the human isolated bronchus
35. The mechanism of action of endothelin on human lung
36. Relationship between endothelin-1 binding site densities and constrictor activities in human and animal airway smooth muscle
37. Endothelin attenuates apoptosis in human smooth muscle cells
38. Activation of guinea pig alveolar macrophages by endothelin-1
39. 4 from mouse bone marrow-derived mast cells
40. Endothelin-1-evoked arachidonic acid release: A Ca(2+)-dependent pathway
41. Production of eicosanoids in response to endothelin-1 and identification of specific endothelin-1 binding sites in airway epithelial cells
42. 4 on human airway smooth muscle cell proliferation, matrix expression, and contraction in vitro: Differential sensitivity to cysteinyl leukotriene receptor antagonists
43. Chemotaxis of human blood monocytes toward endothelin-1 and the influence of calcium channel blockers
44. Characterization of endothelins as chemoattractants for human neutrophils
45. Endothelin-1 and endothelin-3 induce chemotaxis and replication of pulmonary artery fibroblasts
46. Endothelin receptor antagonists inhibit antigen-induced lung inflammation in mice
47. Endothelin production and effects of endothelin antagonism during experimental airway inflammation
48. Mechanisms of endothelin-mediated bronchoconstriction in the guinea pig
49. 4 effects on human eosinophil and neutrophil motility in vitro
50. Leukotriene E4 and granulocytic infiltration in the asthmatic airways
51. Activated eosinophils stimulate endothelin-1 release from airway epithelial cells by direct adherence via adhesion molecules
52. Involvement of endothelins in immediate and late phase asthmatic responses in guinea pigs
53. Endothelin-1 contributes to antigen-induced airway hyperresponsiveness