Influences of indomethacin on contractions induced by endothelins in guinea pig isolated gallbladder

Journal of Cardiovascular Pharmacology

Volumn 36, Issue 5 SUPPL. 1, 2000, Pages

  Nora, H C ^a   Cardozo, A M ^a   D'Orleans Juste, P ^a   Rae, G A ^a  

^a FEDERAL UNIVERSITY OF SANTA CATARINA   (Brazil)

Author keywords

Biliary tract; Contraction; Endothelin (ET); Gallbladder; Guinea pig; Indomethacin; Prostanoid; Smooth muscle

Indexed keywords

CARBACHOL; CYCLO(DEXTRO TRYPTOPHYL DEXTRO ASPARTYLPROLYL DEXTRO VALYLLEUCYL); ENDOTHELIN 1; ENDOTHELIN 3; ENDOTHELIN A RECEPTOR; ENDOTHELIN A RECEPTOR AGONIST; ENDOTHELIN A RECEPTOR ANTAGONIST; ENDOTHELIN B RECEPTOR; ENDOTHELIN B RECEPTOR ANTAGONIST; ICOSANOID; INDOMETACIN; N (2,6 DIMETHYLPIPERIDINOCARBONYL) 4 METHYLLEUCYL DEXTRO (1 METHOXYCARBONYLTRYPTOPHANYL) DEXTRO NORLEUCINE; POTASSIUM CHLORIDE; SARAFOTOXIN S6C;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG ANTAGONISM; GALLBLADDER CONTRACTION; GUINEA PIG; ICOSANOID METABOLISM; MUSCLE ISOMETRIC CONTRACTION; NONHUMAN; PRIORITY JOURNAL;

EID: 0033744354     PISSN: 01602446     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005344-200008000-00010     Document Type: Article

References (10)

1. Endothelin-1 secretion by human gallbladder epithelial cells in primary culture
2. Endothelin-1 is synthesized and inhibits cyclic adenosine monophosphate-dependent anion secretion by an autocrine/paracrine mechanism in gallbladder epithelial cells
3. Endothelin-1 induces cholestasis which is mediated by an increase in portal pressure
4. Endothelin-1 induces contraction of bile canaliculi in isolated rat hepatocytes
5. Effect of endothelin-1 on guinea pig gallbladder smooth muscle in vitro
6. Characterization of endothelin (ET) receptors in the isolated gall bladder of the guinea pig: Evidence for an additional ET receptor subtype
7. Influence of endothelin ET(A) and ET(B) receptor antagonists on endothelin-induced contractions of the guinea pig isolated gall bladder
8. Endothelin receptor subtypes and their role in transmembrane signaling mechanisms
9. 2+ signalling by endothelin receptors in rat and human cultured airway smooth muscle cells
10. Selective activation of excitation-contraction coupling pathways by ET(A) and ET(B) receptors in guinea-pig tracheal smooth muscle